Results 151 to 160 of about 3,780 (219)
[L-dopa and antiparkinson agents].
Delwaide Pj
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Quantitative Determination of Some Synthetic Antiparkinsonism Agents
Journal of Pharmaceutical Sciences, 1968Nonaqueous titrimetry was employed to estimate quantitatively some of the compounds which are useful in treating Parkinsonism. The method was applied to both the crystalline material and their dosage forms. This technique was found to yield results which agreed well with those obtained by either the official procedures or by methods submitted by the ...
L G, Chatten, W J, Racz
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Reactions to Antiparkinson Agents
1987The cardiovascular effects are dose-related. Low doses can cause transient bradycardia; moderate or high doses can cause tachycardia, palpitation, and arrhythmias (due to blockage of vagal effects on the S-A node).
Frank L. Tornatore +3 more
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[Drug information: antiparkinson agents. II. Dopaminergic agents].
Veje Jo
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Some New Piperazino Derivatives as Antiparkinson and Anticonvulsant Agents
Archiv der Pharmazie, 1983AbstractThe piperazino derivatives 1–7 were synthesized and evaluated for their antiparkinson activity on oxotremorine‐induced tremors and reserpine‐induced rigidity. The same compounds were screened for their anticonvulsant activity. Compounds 1, 3, 4 and 5 showed promising antiparkinson activity.
J C, Agarwal +5 more
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Metabolism of antiparkinson agent dopazinol by rat liver microsomes.
Drug Metabolism and Disposition, 1990Metabolism of dopazinol (DZ) by liver microsomes from control and phenobarbital- and 3-methylcholanthrene-treated rats has been investigated. Liver microsomes from control and treated rats metabolized DZ to N-despropyl-DZ (39-53% of total metabolites); 8-hydroxy-DZ, a catechol metabolite (32-39%); and 5- or 6-hydroxy-DZ (12-20%).
K P, Vyas +4 more
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[Considerations on projected pharmacology of antiparkinson agents].
P Duchêne-Marullaz, M Jalfre, J Hache
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Potential antiparkinsonism agents. Quinuclidinyl benzhydryl ethers
Journal of Medicinal Chemistry, 1969J L, Nilsson, J, Wågermark, R, Dahlbom
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