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Antiphospholipid antibodies, antiphospholipid syndrome and infections
Autoimmunity Reviews, 2008Since the association between antiphospholipid antibodies (aPL) and syphilis was first described, many other viral, bacterial and parasitic infections have been shown to induce antiphospholipid antibodies, notably anticardiolipin antibodies (aCL). A review of the literature shows that while aCL occur frequently in viral infections, particularly in HIV (
Jean-Charles Piëtte, Patrice Cacoub
exaly +3 more sources
Noncriteria antiphospholipid antibodies in antiphospholipid syndrome
International Journal of Laboratory HematologyAbstractAntiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic manifestations and/or obstetric complications in patients with persistently positive antiphospholipid antibodies (aPL). aPL are a heterogeneous group of autoantibodies, but only lupus anticoagulant, anticardiolipin (aCL), and antibeta2‐glycoprotein I antibodies
Devreese, Katrien
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Antiphospholipid antibodies and the antiphospholipid antibody syndrome
Drugs of Today, 2000The antiphospholipid antibody syndrome is a multisystem disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia and recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with this ...
G T, Nahass, S L, Jensen
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Australian and New Zealand Journal of Medicine, 1991
This review has focused on some recent developments which have begun to define the immunologic specificity of aPL antibodies. These studies have revealed that these immunoglobulins are more complex than has been realised to date and, more importantly, they offer new approaches to investigate how the prothrombotic diathesis associated with aPL ...
H P, McNeil, S A, Krilis
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This review has focused on some recent developments which have begun to define the immunologic specificity of aPL antibodies. These studies have revealed that these immunoglobulins are more complex than has been realised to date and, more importantly, they offer new approaches to investigate how the prothrombotic diathesis associated with aPL ...
H P, McNeil, S A, Krilis
openaire +2 more sources
Antiphospholipid syndrome, antiphospholipid antibodies, and stroke
International Journal of Stroke, 2023Antiphospholipid syndrome (APS) is a prothrombotic autoimmune disease with heterogeneous clinicopathological manifestations and is a well-established cause of acute ischemic stroke (AIS) and transient ischemic attack (TIA), particularly in younger patients.
Prabal Mittal +5 more
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The Clinical Significance of Antiphospholipid Antibodies
Annals of Medicine, 1997 The antiphospholipid syndrome is defined as the association between the presence of antiphospholipid antibodies, detected as anticardiolipin antibodies and/or lupus anticoagulant, and a history of either arterial or venous thrombosis and/or recurrent ...
Alberto Martini, Angelo Ravelli
exaly +1 more source
The antiphospholipid antibodies
Haematologia, 2001Antiphospholipid antibodies (APLAs) are a group of autoantibodies directed against certain phospholipids, or their protein cofactors. Assay of APLAs is important because their interaction with anionic phospholipid-protein cofactors can generate a syndrome of hypercoagulability associated with a wide variety of thromboembolic events.
Cristina, Tanaseanu +3 more
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