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ANTIPHOSPHOLIPID ANTIBODY SYNDROME

Rheumatic Disease Clinics of North America, 1992
The antiphospholipid syndrome is now well recognized and is separable from SLE, but better quantitation of both the clinical elements and the serologic definitions is still needed. It is likely for autoimmune but not for infection-induced aPL that the antigen is not phospholipid itself but a complex formed by phospholipid and beta 2 glycoprotein I ...
openaire   +3 more sources

Antiphospholipid antibodies and infertility

Human Fertility, 2002
Antiphospholipid antibodies (aPL) are an established cause of recurrent pregnancy loss. As defective embryonic implantation is a common link between unexplained infertility and recurrent miscarriage, interest has focused on the potential relationship between aPL and implantation failure after in vitro fertilization and embryo transfer (IVF-ET).
May, Backos, Raj, Rai, Lesley, Regan
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Antiphospholipid antibodies and the endothelium

Current Rheumatology Reports, 2000
This article reviews current understanding of the relationship between antiphospholipid antibodies and the endothelium. In vitro antiphospholipid antibodies produce endothelial cell activation. Clinical data in this area are scanty and worthy of future research, which could lead to new therapies in the management of antiphospholipid syndrome.
B J, Hunt, M A, Khamashta
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Antiphospholipid antibody syndrome

Current Treatment Options in Cardiovascular Medicine, 2003
Antiphospholipid antibody syndrome (APS) is a recently defined autoimmune disorder characterized by recurrent vascular thromboses or recurrent pregnancy morbidity; these features are linked to the presence in blood of autoantibodies against negatively charged phospholipids or phospholipid-binding proteins.
Elena, Cucurull   +3 more
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Pediatric Antiphospholipid Antibodies and Antiphospholipid Syndrome

Seminars in Thrombosis and Hemostasis, 2008
Antiphospholipid syndrome (APS) can occur in children, like adults, with the same diverse spectrum of thrombotic sites but predominately with deep vein thrombosis and stroke. In contrast with adults, however, transient nonthrombogenic antiphospholipid (aPL) antibodies are seen more commonly, usually after childhood infections.
openaire   +2 more sources

Antiphospholipid antibodies and reproduction

Journal of Reproductive Immunology, 1997
The antiphospholipid antibodies (APA) are acquired antibodies against a phospholipid which has been associated with slow progressive thrombosis and infarction in the placenta. Clinical features (venous or arterial thrombosis, recurrent fetal loss, thrombocytopenia) in conjunction with positive laboratory findings (positive IgG or IgM anticardiolipin ...
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Antiphospholipid Antibodies in Migraine

Headache: The Journal of Head and Face Pain, 1991
SYNOPSIS We studied the presence of serum antiphospholipid antibodies (APA) in 35 patients with migraine and 75 controls. None of the controls showed APA, while we found these antibodies in five patients out of the 35 studied (p=0.003). The clinical features of migraineurs with APA were similar to those of patients without them. After
C, Iñiguez   +4 more
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Antiphospholipid Antibody Syndrome

Obstetrics and Gynecology Clinics of North America, 2014
Antiphospholipid antibodies (aPLs) are acquired antibodies directed against negatively charged phospholipids. Obstetric antiphospholipid antibody syndrome (APS) is diagnosed in the presence of certain clinical features in conjunction with positive laboratory findings.
William H, Kutteh, Candace D, Hinote
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Antiphospholipid antibody syndrome

Current Treatment Options in Neurology, 2000
When the diagnosis of antiphospholipid antibody syndrome (aPS) is being considered in persons who have experienced an ischemic stroke or a transient ischemic attack, it is important to gauge how well the history and laboratory data fit with this diagnosis as opposed to other causes of infarct.
, Jacobs, , Levine
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Antiphospholipid antibodies and stroke

Current Cardiology Reports, 2004
Antiphospholipid antibodies are associated with venous and arterial thrombo-occlusive events, including stroke. They are a heterogeneous family of antibodies that react to negatively charged membrane-bound phospholipids or phospholipid-protein complexes.
openaire   +2 more sources

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