Results 21 to 30 of about 554,154 (221)

Patient-derived anti-β2GP1 antibodies recognize a peptide motif pattern and not a specific sequence of residues

Haematologica, 2017
Antiphospholipid antibody syndrome is an autoimmune disease characterized by the presence of so-called antiphospholipid antibodies and clinical manifestations such as recurrent thromboembolic or pregnancy complications.
Philippe de Moerloose, Céline Fickentscher, Françoise Boehlen, Jean-Marie Tiercy, Egbert K.O. Kruithof, Karim J. Brandt   +5 more
doaj   +1 more source

Clinical significance of antibodies to the phosphatidylserine/prothrombin complex

Современная ревматология, 2022
Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant.
T. M. Reshetnyak, F. A. Cheldieva, M. V. Cherkasova, A. M. Lila   +3 more
doaj   +1 more source

Increased heterogeneity of brain perfusion is an early marker of central nervous system involvement in antiphospholipid antibody carriers. [PDF]

PLoS ONE, 2017
The non-criteria neuropsychiatric manifestations of antiphospholipid syndrome include headache, dizziness, vertigo, seizure, depression and psychosis. There were still no objective methods qualified to detect the early central nervous system involvement ...
Ting-Syuan Lin, Pei-Ying Hsu, Chin-Hao Chang, Chi-Lun Ko, Yu-Min Kuo, Yen-Wen Wu, Ruoh-Fang Yen, Cheng-Han Wu, Ko-Jen Li, Yenh-Chen Hsein, Song-Chou Hsieh   +10 more
doaj   +1 more source

Patients with Essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis [PDF]

, 2002
A significant proportion of patients with Essential Thrombocythaemia (ET) have thrombotic complications which have an important impact upon the quality, and duration of their life.
Machin, S.J., C.N. Harrison, P. Carr, Mackie, I., Donohoe, S., S.J. Machin, S. Donohoe, I. Mackie, M. Dave, Harrison, C.N., Dave, M., Carr, P.   +11 more
core   +1 more source

A role for uric acid and the nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast [PDF]

, 2013
Women with antiphospholipid syndrome (APS) are at risk of recurrent pregnancy loss and obstetrical disorders, such as preeclampsia and intrauterine growth restriction (IUGR).
Vikki M Abrahams, Kavathas, Paula B., Melissa J Mulla, Crina M Boeras, Mulla, Melissa J., Paula B Kavathas, Jan J Brosens, Brosens, Jan J., Boeras, Crina M., Larry W Chamley, Jane E Salmon, Abrahams, Vikki M., Salmon, Jane E., Chamley, Larry W., Boeras Crina M., Chamley Larry W., Abrahams Vikki M., Mulla Melissa J., Salmon Jane E., Brosens Jan J., Kavathas Paula B.   +20 more
core   +2 more sources

The Pathophysiology of The Antiphospholipid Syndrome: A Perspective From The Blood Coagulation System

Clinical and Applied Thrombosis/Hemostasis, 2022
The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused by the presence of antiphospholipid antibodies such as lupus anticoagulant ...
R Arreola-Diaz MSc, A Majluf-Cruz MD, PhD, LE Sanchez-Torres PhD, J Hernandez-Juarez PhD   +3 more
doaj   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies. [PDF]

Int J Gynaecol Obstet
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Yang T, Okada E, Todoroki M, Liu S, Athurupana R, Kataoka K, Kashino C, Mitsui T, Hasegawa T, Kamada Y, Masuyama H, Nakatsuka M.   +11 more
europepmc   +2 more sources

Prevalence and clinical significance of antiphospholipid antibodies among hospitalized COVID-19 patients

Asian Pacific Journal of Tropical Medicine, 2021
Objective: To describe the prevalence of antiphospholipid antibodies in coronavirus disease-19 (COVID-19) and to find potential associations between antiphospholipid antibody positivity and clinical outcomes.
Cesarius Singgih Wahono, Hani Susianti, Tri Wahyudi Iman Dantara, Perdana Aditya Rahman, Mirza Zaka Pratama, Indah Adhita Wulanda, Khoirunisah Dwi Hartanti, Elvira Sari Dewi, Kusworini Handono   +8 more
doaj   +1 more source

Deep capillary retinal ischemia and high-titer prothrombin-associated antiphospholipid antibodies: A case series of three patients

American Journal of Ophthalmology Case Reports, 2019
Purpose: Acute macular neuroretinopathy has been shown to be due to ischemia of the deep capillary retinal plexus and most cases occur in young women; we hypothesized that there may be an association with antiphospholipid antibodies.
Jill R. Schofield, Alan G. Palestine, Victoria Pelak, Marc T. Mathias   +3 more
doaj   +1 more source

Hypermetabolism of basal ganglia in chorea associated with antiphospholipid antibodies demonstrated by F-18 FDG

South African Journal of Radiology, 1997
A brain FDG PET study was performed on a 21-year-old woman with subacute chorea of unknown origin. Associated with her chorea, she had abnormal levels of antiphospholipid antibodies.
M. M. Sathekge, A. Maes, V. Thijst, M. de Roo   +3 more
doaj   +1 more source