Results 41 to 50 of about 22,831 (195)

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

iMeta, EarlyView.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang, Hongli Zhao, Xinyi Ding, Haoling Zhang, Yadong Guo, Yiming Ma, Lingyi Cai, Qingnan Fan, Ruisi Peng, Fuyuan Yang, Doblin Sandai, Xianling Cao, Jiali Yao, Wenyi Wang, Zhiheng Lin, Wangzheqi Zhang, Jialin He, Aihua Zhang, Xiaoxuan Zhao   +18 more
wiley   +1 more source

ANTIPHOSPHOLIPID SYNDROME IN OBJECTIVE PRACTICE

Мать и дитя в Кузбассе, 2018
The aim of the study – to study the spectrum of antiphospholipid antibodies in patients with fetal loss syndrome living in the Omsk region. Materials and methods. 80 patients with a history of fetal loss were examined. Results.
Анастасия Александровна Гончарова, Елена Николаевна Кравченко, Галина Владимировна Кривчик, Ирина Рахимжановна Вотрина, Вилена Юрьевна Чебакова   +4 more
doaj  

Granulomatosis with Polyangiitis (Wegener’s Granulomatosis) Co-Existing with Antiphospholipid Syndrome – An Unusual Cutaneous Presentation

Pakistan Journal of Medicine and Dentistry
Granulomatosis with polyangiitis (GPA) is an autoimmune disease that causes inflammation of the small blood vessels and involves many organs, most commonly the upper and lower respiratory tracts and the kidneys. GPA can also affect other organs, such as
Neha Rana, Humaira Talat, Maryam Rehan, Reema Mirza, Batool ur Rehman   +4 more
doaj   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Catastrophic antiphospholipid syndrome with eosinophilia mimicking hypereosinophilic syndromes with disseminated intravascular coagulation: a case report

Journal of Medical Case Reports
Background Catastrophic antiphospholipid syndrome is a rare variant of antiphospholipid syndrome where the presence of antiphospholipid antibodies and systemic inflammation leads to the rapid onset of multifocal thrombosis.
Hikari Ota, Tomoyuki Yoshizaki, Satoshi Nakayama, Rintaro Wakamiya, Ayano Matsunaga, Hiroaki Takeo, Kazuhiro Masuoka   +6 more
doaj   +1 more source

Etanercept and venous thromboembolism: a case series

Journal of Medical Case Reports, 2010
Introduction The treatment with antitumor necrosis factor agents has often been associated with the induction of autoantibodies (antinuclear antibodies, anti-double stranded DNA antibodies and antiphospholipid antibodies).
Guggenheim Carla, Grover Madhusudan, Makol Ashima, Hassouna Houria   +3 more
doaj   +1 more source

TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu, Ling‐Jung Yen, Hui‐Ling Hsia, Zi‐Xeng Weng, Chi‐Hsiang Chung, Paul Wei‐Che Hsu, Chih‐Wei Chiu, Wu‐Chien Chien, Tsung‐Hsien Chang   +8 more
wiley   +1 more source

Anticoagulantes Lúpicos versus Anticorpos Antifosfolípidos.

Acta Médica Portuguesa, 1998
The antiphospholipid antibodies (aPL) present in "antiphospholipid-protein syndrome and autoimmune disorders" are associated with thromboembolic episodes, such as venous and/or arterial thrombosis and fetal loss. Patients with antiphospholipid antibodies
M I Pereira
doaj   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

Antiphospholipid antibodies [PDF]

Vascular Medicine, 2017
Damon E, Houghton, Stephan, Moll
openaire   +4 more sources