Results 71 to 80 of about 513,178 (237)

A pro‐inflammatory cytokine signature characterises thrombotic antiphospholipid syndrome despite stable anticoagulation

British Journal of Haematology, EarlyView.
Primary antiphospholipid syndrome comprises distinct inflammatory subgroups defined by cytokine profiling. A shared pro‐inflammatory signature is present across all patients, whereas arterial thrombosis demonstrates enhanced inflammatory activation compared with venous thrombosis, suggesting divergent pathogenic mechanisms and opportunities for ...
Catherine B. Ducker, Megan V. Preece, Jeremy Schofield, Charis Pericleous, Mike Laffan, Simon Abrams, Deepa J. Arachchillage   +6 more
wiley   +1 more source

Antiphospholipid Antibodies and Syndrome [PDF]

, 2018
Antiphospholipid syndrome (APS) is an autoimmune disorder caused by antiphospholipid antibodies. It was characterized by excessive clotting of blood and/or certain complications of pregnancy (premature miscarriages, unexplained fetal death, or premature ...
Ricard Cervera (Ed.)
core   +1 more source

Chorea Associated with High Titers of Antiphospholipid Antibodies in the Absence of Antiphospholipid Antibody Syndrome

Tremor and Other Hyperkinetic Movements, 2015
Background: Chorea associated with high titers of antiphospholipid antibodies in the absence of antiphospholipid antibody syndrome has been seldom reported.Case report: An 89-year-old female developed persistent right side chorea associated with high ...
Damoun Safarpour, Sarah Buckingham, Bahman Jabbari   +2 more
doaj   +1 more source

An Atypical Skin Presentation of Adult‐Onset Still's Disease With Histological Description: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann, T. Mazza, S. Menzinger, G. Kaya, S. Bogiatzi, S. Vandenberghe‐Dürr, M. Blanchard, J. Stirnemann   +7 more
wiley   +1 more source

Disseminated intravascular coagulation and antiphospholipid antibodies in systemic lupus erythematosus

, 2000
Papers and abstract from International symposium on Antiphospholipid Antibodies.
FERRI, Giovanni Maria, VACCARO, Francesco, ROSSI FANELLI, Filippo, GIORGI, Antonella, LAGANA', Bruno, PACE F, GUBITOSI G   +6 more
core  

Intima‐Media Thickness Progression Rate and Primary Unassisted Patency Failure in Arteriovenous Fistulas: A Prospective Cohort Study

Hemodialysis International, EarlyView.
ABSTRACT Background Failure of autogenous arteriovenous fistulas (AV fistulas) due to venous neointimal hyperplasia is a major clinical challenge. Whether the rate of progression in venous intima‐media thickness predicts primary unassisted patency failure remains unknown.
Gen Li, Zhengjiang Cao
wiley   +1 more source

Chorea as a sign of systemic lupus erythematosus activity: case report

Arquivos de Neuro-Psiquiatria, 1993
Chorea may occur as a neurological manifestation of systemic lupus erythematosus and is often associated with detection of antiphospholipid antibodies. No evidence of chorea as a sign of lupus activity has been established.
P. Caramelli, S.M. Toledo, P.E. Marchiori, E.R. Barbosa, M. Scaff   +4 more
doaj   +1 more source

Prevalence and Risk Factors of Systemic Lupus Erythematosus in Patients With Chronic Cutaneous Lupus: A Bicentric Study Employing Three Classification Criteria

International Journal of Dermatology, EarlyView.
This bicentric study of 95 CCLE patients shows SLE prevalence (21.1%–31.6%) varies significantly by classification criteria. Arthralgia was a consistent independent risk factor across all systems. Our findings support the implementation of systematic risk‐stratified screening protocols for CCLE patients, with particular attention to joint symptoms and ...
Noureddine Litaiem, Syrine Nahali, Maroua Slouma, Mourad Mokni, Faten Zeglaoui   +4 more
wiley   +1 more source

Performance Assessment of Staclot‐LA Assay on Fully Automated Coagulation Analyser for Lupus Anticoagulant Testing Using Internal and External Quality Controls

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction It is recommended to detect lupus anticoagulant (LA) using two phospholipid‐dependent clotting assays, including a LA‐sensitive activated partial‐thromboplastin‐time (aPTT). Among these reagents, Staclot‐LA assay is performed on a mixture of test and normal plasma with and without hexagonal phase phospholipids.
V. Siguret, G. Jourdi, S. Melicine, L. Goubeau, Q. Pomorski, B. Joly‐Laffargue, A. Stepanian, M. Delrue, C. Bon, P. Meijer, E. Curis   +10 more
wiley   +1 more source

Functional Assessment of Platelet‐Derived Phospholipid Activity in Pooled Normal Plasmas by Low‐Phospholipid Thrombin Generation Assay and Its Impact on Lupus Anticoagulant Mixing Tests

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Pooled normal plasma (PNP) used for lupus anticoagulant (LA) mixing tests may carry platelet‐derived phospholipid (PL) activity introduced during freezing/lyophilization, potentially attenuating LA‐mediated prolongation of clotting times.
Osamu Kumano, Masato Matsuda, Mino Sakata, Osamu Maruyama   +3 more
wiley   +1 more source