Implications of Antiphospholipid and Antineutrophilic Cytoplasmic Antibodies in the Context of Postinfectious Glomerulonephritis. [PDF]
While antineutrophil cytoplasmic antibody (ANCA) positivity has been documented in some patients with postinfectious glomerulonephritis (PIGN) and is associated with more severe disease, antiphospholipid antibodies (APA) are not known to be a common ...
Butani, Lavjay, Leifer, Daniel
core +4 more sources
Antiphospholipid antibody syndrome is an autoimmune disease characterized by the presence of so-called antiphospholipid antibodies and clinical manifestations such as recurrent thromboembolic or pregnancy complications.
Philippe de Moerloose +5 more
doaj +1 more source
Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
Increased heterogeneity of brain perfusion is an early marker of central nervous system involvement in antiphospholipid antibody carriers. [PDF]
The non-criteria neuropsychiatric manifestations of antiphospholipid syndrome include headache, dizziness, vertigo, seizure, depression and psychosis. There were still no objective methods qualified to detect the early central nervous system involvement ...
Ting-Syuan Lin +10 more
doaj +1 more source
Background The kidney is a major target in primary antiphospholipid syndrome. Several types of nephropathy have been reported, the most frequent being acute or chronic specific vascular nephropathies and membranous nephropathy.
Maxime Teisseyre +6 more
doaj +1 more source
Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]
Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Giles, I. +7 more
core +1 more source
High frequency of inadequate test requests for antiphospholipid antibodies in daily clinical practice [PDF]
Background: We have empirically noted that many physicians routinely request anti-phospholipid antibodies (aPL) without a correct clinical indication. The aim of this study was to evaluate retrospectively whether aPL testing at our Thrombosis Centre was ...
Barcellona D +3 more
core +1 more source
An Approach to Differential Diagnosis of Antiphospholipid Antibody Syndrome and Related Conditions
The antiphospholipid antibody syndrome is a systemic, acquired, immune-mediated disorder characterized by episodes of venous, arterial, or microcirculation thrombosis and/or pregnancy abnormalities, associated with the persistent presence of ...
Giacomo Emmi +9 more
doaj +1 more source
Background: The management of patients with recurrent miscarriage (RM) and antiphospholipid antibody syndrome (APS) includes prolonged treatment with heparin and aspirin, starting from the confirmation of pregnancy and continuing until 6 weeks after ...
Yu Song +4 more
doaj +1 more source
The Risk of Thrombotic Events in Anetoderma Affecting Young Patients
Anetoderma is a rare skin disease, and its associated risk of thromboembolic events is unknown. Anetoderma is characterized by focal injury of elastic fibers in the dermis, clinically expressed by atrophic skin lesions.
Chiriac Anca E. +3 more
doaj +1 more source

