Results 161 to 170 of about 19,639 (215)

Persistent Moderate-to-High Levels of Isolated Anticardiolipin Antibody IgA or Anti-β2-Glycoprotein-I IgA Isotypes: Do They Have Any Clinical Relevance?

Turkish Journal of Hematology
Ayşe Bahar Keleşoğlu Dinçer, Jonathan Thaler, Doruk Erkan   +2 more
doaj   +1 more source

Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study [PDF]

American Journal of Obstetrics and Gynecology, 2017
BACKGROUND: Antiphospholipid syndrome is an autoimmune, hypercoagulable state that is caused by antiphospholipid antibodies. Anticardiolipin antibodies, anti-β2 glycoprotein-I, and lupus anticoagulant are the main autoantibodies found in ...
Gabriele Saccone, Vincenzo Berghella, Giuseppe Maria Maruotti   +2 more
exaly   +5 more sources

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Antiphospholipid antibodies and the antiphospholipid syndrome

Springer Seminars in Immunopathology, 1994
The study of aPL antibodies and the APS has appealed to large numbers of investigators over the last decade. This accounts, in part, for the great degree of apparently contradictory data being published. What seems certain is that these antibodies are associated with thrombosis and recurrent pregnancy loss, and animal data suggest a direct role in ...
E N, Harris, S S, Pierangeli
openaire   +4 more sources

Antiphospholipid antibodies and the antiphospholipid antibody syndrome

Drugs of Today, 2000
The antiphospholipid antibody syndrome is a multisystem disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia and recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with this ...
G T, Nahass, S L, Jensen
openaire   +2 more sources

Antiphospholipid Antibodies and Reproduction: The Antiphospholipid Antibody Syndrome

American Journal of Reproductive Immunology, 1999
In women who have a diagnosis of APS (both clinical and laboratory criteria) the chance for successful pregnancy is reduced. In these cases, treatment appears to be a clear option, particularly in the case of prior thromboembolic events. The current preference of treatment for women with RPL and aPL antibodies is subcutaneous heparin and aspirin.
William H Kutteh, Neal S Rote, Robert M Silver   +2 more
exaly   +3 more sources

Antiphospholipid antibodies and antiphospholipid syndrome

Current Opinion in Rheumatology, 1995
More than a decade has gone by since the detailed clinical description of antiphospholipid syndrome (APS). Thrombosis, the main complication of the syndrome, can affect vessels of all sizes; the consistent histopathologic lesion is a bland thrombus without inflammation.
M A, Khamashta, G R, Hughes
openaire   +2 more sources

Antiphospholipid syndrome, antiphospholipid antibodies, and stroke

International Journal of Stroke, 2023
Antiphospholipid syndrome (APS) is a prothrombotic autoimmune disease with heterogeneous clinicopathological manifestations and is a well-established cause of acute ischemic stroke (AIS) and transient ischemic attack (TIA), particularly in younger patients.
Prabal Mittal, Graziella Quattrocchi, Ibrahim Tohidi-Esfahani, Zara Sayar, Arvind Chandratheva, Hannah Cohen   +5 more
openaire   +2 more sources

Antiphospholipid antibody syndrome

Current Treatment Options in Cardiovascular Medicine, 2003
Antiphospholipid antibody syndrome (APS) is a recently defined autoimmune disorder characterized by recurrent vascular thromboses or recurrent pregnancy morbidity; these features are linked to the presence in blood of autoantibodies against negatively charged phospholipids or phospholipid-binding proteins.
Elena, Cucurull, Azzudin E., Gharavi, Yamini, Menon, Wendell A., Wilson   +3 more
openaire   +2 more sources

Antiphospholipid Antibody Syndrome

Obstetrics and Gynecology Clinics of North America, 2014
Antiphospholipid antibodies (aPLs) are acquired antibodies directed against negatively charged phospholipids. Obstetric antiphospholipid antibody syndrome (APS) is diagnosed in the presence of certain clinical features in conjunction with positive laboratory findings.
William H, Kutteh, Candace D, Hinote
openaire   +2 more sources

Antiphospholipid antibody syndrome

Current Treatment Options in Neurology, 2000
When the diagnosis of antiphospholipid antibody syndrome (aPS) is being considered in persons who have experienced an ischemic stroke or a transient ischemic attack, it is important to gauge how well the history and laboratory data fit with this diagnosis as opposed to other causes of infarct.
, Jacobs, , Levine
openaire   +2 more sources