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Antiphospholipid Syndrome and the Kidney [PDF]

Kidney International Reports
Antiphospholipid syndrome (APS) is a rare autoimmune disorder characterized by the persistent positivity of antiphospholipid antibodies (aPLs) along with thrombotic manifestations, obstetrical complications, or nonthrombotic manifestations. The kidney is
Maxime Taghavi, Lucas Jacobs, Dario Roccatello, Savino Sciascia   +3 more
doaj   +2 more sources

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

Nature Communications, 2019
Antiphospholipid syndrome is characterised by increased neutrophil extracellular trap formation (NETosis) and, consequently, increased thrombotic events. Here Ali et al.
Ramadan A. Ali, Alex A. Gandhi, He Meng, Srilakshmi Yalavarthi, Andrew P. Vreede, Shanea K. Estes, Olivia R. Palmer, Paula L. Bockenstedt, David J. Pinsky, Joan M. Greve, Jose A. Diaz, Yogendra Kanthi, Jason S. Knight   +12 more
doaj   +2 more sources

Cerebral Vein Thrombosis in the Antiphospholipid Syndrome: Analysis of a Series of 27 Patients and Review of the Literature

Brain Sciences, 2021
(1) Background: The Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, pregnancy morbidity and raised titers of antiphospholipid antibodies.
Alba Jerez-Lienas, Alexis Mathian, Jenifer Aboab, Isabelle Crassard, Miguel Hie, Fleur Cohen-Aubart, Julien Haroche, Denis Wahl, Ricard Cervera, Zahir Amoura   +9 more
doaj   +1 more source

Direct-acting oral anticoagulants in antiphospholipid syndrome

Научно-практическая ревматология, 2021
Antiphospholipid syndrome is an acquired autoimmune thrombophilia characterized by the development of recurrent vascular thrombosis of any caliber and type or obstetric pathology and the mandatory identification of persistently positive antiphospholipid ...
T. M. Reshetnyak, K. S. Nurbaeva
doaj   +1 more source

2023 ACR/EULAR antiphospholipid syndrome classification criteria

Arthritis & Rheumatology, 2023
Objective To develop new antiphospholipid syndrome (APS) classification criteria with high specificity for use in observational studies and trials, jointly supported by the American College of Rheumatology (ACR) and EULAR.
M. Barbhaiya, S. Zuily, R. Naden, Alison M Hendry, F. Manneville, M. Amigo, Z. Amoura, D. Andrade, L. Andreoli, B. Artım-Esen, T. Atsumi, T. Avčin, M. Belmont, M. Bertolaccini, D. Branch, G. Carvalheiras, A. Casini, R. Cervera, Hannah Cohen, N. Costedoat-Chalumeau, M. Crowther, G. D. de Jesús, A. Delluc, S. Desai, M. D. De Sancho, K. Devreese, R. Diz‐Kucukkaya, A. Duarte-García, C. Francès, David A. Garcia, J. Gris, N. Jordan, R. K. Leaf, N. Kello, J. Knight, C. Laskin, A. Lee, K. Legault, Steve R Levine, R. Levy, M. Limper, M. Lockshin, K. Mayer-Pickel, J. Musial, P. Meroni, G. Orsolini, T. Ortel, V. Pengo, M. Petri, G. Pons-Estel, José A. Gómez-Puerta, Quentin Raimboug, R. Roubey, G. Sanna, S. Seshan, S. Sciascia, Maria G. Tektonidou, A. Tincani, D. Wahl, R. Willis, C. Yelnik, C. Zuily, F. Guillemin, K. Costenbader, D. Erkan   +64 more
semanticscholar   +1 more source

Consequences of antiphospholipid syndrome in pregnancy - A review [PDF]

Romanian Journal of Rheumatology, 2023
Background and objectives. Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies (aPL) in the blood.
Astrit M. Gash
doaj   +1 more source

EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome

Annals of the Rheumatic Diseases, 2022
Objective To develop recommendations for cardiovascular risk (CVR) management in gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren’s syndrome (SS), systemic lupus erythematosus (SLE) and ...
G. Drosos, D. Vedder, E. Houben, L. Boekel, F. Atzeni, S. Badreh, D. Boumpas, N. Brodin, I. Bruce, M. González-Gay, S. Jacobsen, G. Kerekes, F. Marchiori, C. Mukhtyar, M. Ramos-Casals, N. Sattar, K. Schreiber, S. Sciascia, E. Svenungsson, Z. Szekanecz, A. Tausche, A. Tyndall, V. van Halm, A. Voskuyl, G. Macfarlane, M. Ward, M. Nurmohamed, Maria G. Tektonidou   +27 more
semanticscholar   +1 more source

Antiphospholipid Syndrome in Pregnancy: New and Old Pathogenetic Mechanisms

International Journal of Molecular Sciences, 2023
The antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized, according to the Sydney criteria, by the persistent presence of autoantibodies directed against phospholipid-binding proteins associated with thrombosis and/or ...
S. D’Ippolito, Greta Barbaro, Carmela Paciullo, C. Tersigni, Giovanni Scambia, N. Di Simone   +5 more
semanticscholar   +1 more source

Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

Seminars in Immunopathology, 2022
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications.
J. Knight, Y. Kanthi
semanticscholar   +1 more source

Pathogenesis, Diagnosis and Management of Obstetric Antiphospholipid Syndrome: A Comprehensive Review

Journal of Clinical Medicine, 2022
Antiphospholipid syndrome is an autoimmune disorder characterized by vascular thrombosis and/or pregnancy morbidity associated with persistent antiphospholipid antibody positivity.
J. Alijotas-Reig, E. Esteve-Valverde, A. Anunciación-Llunell, J. Marques-Soares, J. Pardos-Gea, F. Miró-Mur   +5 more
semanticscholar   +1 more source