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Antiphospholipid Syndrome [PDF]

open access: yesTranslational Research, 2008
Antiphospholipid syndrome is one of the more common acquired causes of hypercoagulability. Its major presentations are thrombotic (arterial, venous, or microvascular) and pregnancy morbidity (miscarriages, late intrauterine fetal demise, and severe pre-eclampsia).
Cervera, Ricard, Espinosa, Gerard
openaire   +6 more sources

Epidemiology of Antiphospholipid Syndrome in the General Population

open access: yesCurrent Rheumatology Reports, 2021
Purpose of Review The epidemiology of antiphospholipid syndrome (APS) is poorly understood. Here, we review the current understanding of the epidemiology of antiphospholipid syndrome in the general population and the frequency of antiphospholipid ...
Jesse Y Dabit   +3 more
semanticscholar   +1 more source

Antiphospholipid Syndrome [PDF]

open access: yesBest Practice & Research Clinical Rheumatology, 2016
Antiphospholipid syndrome (APS) is an autoimmune condition characterized by the occurrence of thrombosis (arterial and/or venous), often multiple, and/or pregnancy morbidity. Thrombosis is one of the major disease mechanisms, mainly caused by activating endothelial cells, monocytes, and platelets.
Khamashta, M.   +3 more
openaire   +5 more sources

The Screening of Antiphospholipid Antibodies in Obstetric Antiphospholipid Syndrome-Like Events: A Regional Perspective

open access: yesGynecology Obstetrics & Reproductive Medicine, 2020
Objective: Obstetric antiphospholipid antibody syndrome is clinically recognized by adverse obstetric outcomes. To determine which antibody level best corresponds to the risk of these clinical outcomes is difficult.
Onder Onen, Fusun Gulizar Varol
doaj   +1 more source

The Pathophysiology of The Antiphospholipid Syndrome: A Perspective From The Blood Coagulation System

open access: yesClinical and applied thrombosis/hemostasis, 2022
The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused by the presence of antiphospholipid antibodies such as lupus anticoagulant ...
R. Arreola-Diaz   +3 more
semanticscholar   +1 more source

Impact of nitric oxide synthesis modulators on the state of humoral immune system in experimental antiphospholipid syndrome [PDF]

open access: yesPharmacia, 2023
Background: Antiphospholipid syndrome is an autoimmune disease of multiple venous and/or arterial thrombosis and/or pregnancy loss. Oxidative stress only enhances the body’s immune response.
Nataliia Mekhno, Olha Yaremchuk
doaj   +3 more sources

Added value of antiphosphatidylserine/prothrombin antibodies in the workup of thrombotic antiphospholipid syndrome: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

open access: yesJournal of Thrombosis and Haemostasis, 2022
Diagnosis of antiphospholipid syndrome (APS) requires persistent presence of lupus anticoagulant (LAC), anticardiolipin (aCL) IgG/IgM, or anti‐β2 glycoprotein I (aβ2GPI) IgG/IgM antibodies.
A. Vandevelde   +7 more
semanticscholar   +1 more source

Primary antiphospholipid syndrome associated with anti-phospholipase A2 receptor antibody-positive membranous nephropathy

open access: yesBMC Nephrology, 2020
Background The kidney is a major target in primary antiphospholipid syndrome. Several types of nephropathy have been reported, the most frequent being acute or chronic specific vascular nephropathies and membranous nephropathy.
Maxime Teisseyre   +6 more
doaj   +1 more source

Antiphospholipid Syndrome

open access: yesThrombosis Research, 2017
The antiphospholipid syndrome (APS) is defined by the development of venous and/or arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses), in the presence of antiphospholipid antibodies (aPL). Some estimates indicate that the incidence of the APS is around 5 new cases per 100,000 persons per year and the ...
R. Cervera
semanticscholar   +3 more sources

Antiphospholipid Syndrome

open access: yesInternational Archives of Allergy and Immunology, 2000
Antiphospholipid syndrome (APS) is a disease characterized by venous and arterial thromboses or spontaneous abortions and the repeated detection of antiphospholipid antibodies (aPL). APS may be associated with another autoimmune disease (secondary APS), particularly systemic lupus erythematosus (SLE), or unrelated to an underlying disease (primary APS).
E, Gromnica-Ihle, W, Schössler
  +7 more sources

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