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Antiphospholipid syndrome

Hematology, 2013
Abstract The antiphospholipid syndrome (APS) is defined by venous or arterial thrombosis and/or pregnancy morbidity in patients with persistent presence of antiphospholipid antibodies (aPLs). Catastrophic APS is the most severe form of APS, which is associated with rapid development of microvascular thrombosis resulting in multiorgan ...
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Antiphospholipid syndrome

Thrombosis Research, 2017
The antiphospholipid syndrome (APS) is defined by the development of venous and/or arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses), in the presence of antiphospholipid antibodies (aPL). Some estimates indicate that the incidence of the APS is around 5 new cases per 100,000 persons per year and the ...
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Antiphospholipid syndrome

Best Practice & Research Clinical Rheumatology, 2020
Antiphospholipid syndrome is an autoimmune systemic disorder characterized by arterial, venous, or small vessel thrombosis and/or recurrent early pregnancy loss, fetal loss, or pregnancy morbidity in the setting of documented persistent antiphospholipid antibodies that include the lupus anticoagulant, or moderate-high titer anticardiolipin, or anti ...
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Antiphospholipid Syndrome

Progress in Cardiovascular Diseases, 2009
The antiphospholipid syndrome (APS) is an autoimmune systemic disease that is diagnosed when there is vascular thrombosis and/or pregnancy morbidity occurring with persistently positive antiphospholipid antibodies (aPL) (lupus anticoagulant test, anticardiolipin antibodies, and/or anti-beta(2)-glycoprotein I antibodies).
Diane, George, Doruk, Erkan
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Antiphospholipid antibodies and antiphospholipid syndrome

Current Opinion in Rheumatology, 1995
More than a decade has gone by since the detailed clinical description of antiphospholipid syndrome (APS). Thrombosis, the main complication of the syndrome, can affect vessels of all sizes; the consistent histopathologic lesion is a bland thrombus without inflammation.
M A, Khamashta, G R, Hughes
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Pediatric Antiphospholipid Syndrome

Current Rheumatology Reports, 2015
Antiphospholipid syndrome (APS) is a multisystem autoimmune condition characterized by vascular thromboses associated with persistently positive antiphospholipid antibodies. There is currently a paucity of data (incidence, prevalence, thrombosis risk, and effective treatment) in pediatric APS.
Cassyanne L, Aguiar   +3 more
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Antiphospholipid Antibody Syndrome

Current Opinion in Ophthalmology, 2012
Antiphospholipid antibody (APLA) syndrome (APS) is a heterogeneous disorder defined by the finding of persistent APLA in patients with arterial or venous thrombosis or pregnancy morbidity. APS manifestations range from deep vein thrombosis to stroke and even rapid multiorgan failure (the rare catastrophic APS).
Zambon M., Cappelli D., Berlot G.
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Catastrophic antiphospholipid syndrome

Current Opinion in Hematology, 2000
In its classic presentation, the antiphospholipid syndrome manifests a combination of venous or arterial thrombosis and fetal loss, accompanied by elevations of antibodies directed toward negatively charged phospholipids, as measured by anticardiolipin antibody assays and/or positive lupus anticoagulant tests.
Ronald A, Asherson, Ricard, Cervera
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Antiphospholipid Syndrome

Vascular Medicine Review, 1994
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Catastrophic Antiphospholipid Syndrome

Journal of Intensive Care Medicine, 2006
Catastrophic antiphospholipid syndrome is a rapidly progressive life-threatening disease that causes multiple organ thromboses and dysfunction in the presence of antiphospholipid antibodies. A high index of clinical suspicion and careful investigation are required to make an early diagnosis so that treatment with anticoagulation and corticosteroids ...
Setu K, Vora   +2 more
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