Results 51 to 60 of about 143,360 (302)

Antithrombotic therapy after transcatheter aortic valve replacement

Heart Views, 2022
Transcatheter aortic valve replacement (TAVR) is a treatment option for patients with asymptomatic severe aortic stenosis who are candidates for a bioprosthesis across the entire spectrum of risk.
Tariq A.M. Mousa, Ahmed Mahfouz, Nazar Mohammed   +2 more
doaj   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE).
Sarah L. Patterson, Russell Ellyson, Jessica Fitzpatrick, Ghizlane Yaakoubi, Bradley Pearce, S. Sam Lim, Jinoos Yazdany, Laura C. Plantinga   +7 more
wiley   +1 more source

Bleeding complications related to external ventricular drainage placement in patients with ruptured intracranial aneurysms: a single-center study

Frontiers in Surgery
ObjectiveAcute aneurysmal rupture can be treated with endovascular therapy or surgical clipping. For patients with concurrent acute hydrocephalus, the placement of an external ventricular drainage (EVD) is required.
Yue Tang, Xiangping Zhong, Tingting Lin, Fujun Zuo, Min Fu, Li Wang, Xiaodu Yu, Dong Liu, Jincan Zhang   +8 more
doaj   +1 more source

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao, Qinying Han, Yunpeng Wang, Xuemei Li, Bofang Wang, Baohong Gu, Weidong Li, Lin Xiang, Ying Zhang, Hao Chen   +9 more
wiley   +1 more source

Major Bleeding Events in Hospitalized COVID-19 Patients: A Retrospective Observational Study

Medicina
Thromboprophylaxis/anticoagulation treatment is often required in hospitalized COVID-19 patients. We aimed to estimate the prevalence of major bleeding events in hospitalized COVID-19 patients.
Andrea Poloni, Giacomo Casalini, Giacomo Pozza, Andrea Giacomelli, Marta Colaneri, Giorgia Carrozzo, Beatrice Caloni, Cosmin Lucian Ciubotariu, Martina Zacheo, Andrea Rabbione, Margherita Pieruzzi, Federico Barone, Matteo Passerini, Anna Lisa Ridolfo, Giuliano Rizzardini, Andrea Gori, Spinello Antinori   +16 more
doaj   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

How to undertake procedures while on antiplatelet agents: a hematologist's view

Research and Practice in Thrombosis and Haemostasis
Cardiovascular diseases (CVDs) are the leading cause of mortality globally while also contributing to excess health system costs. Significant advancements have been made in the understanding and prevention of deaths from CVD.
Dawn Swan, Robert Turner, James Douketis, Jecko Thachil   +3 more
doaj   +1 more source

Pharmacogenetics of Antiplatelet Drugs [PDF]

The Scientific World JOURNAL, 2002
Pharmacogenetics refers to the genetic factors that influence the response to a drug, often involving genetic variations in drug metabolizing enzymes. The pharmacogenetics of antiplatelet agents is in its infancy and largely reflects variations in drug targets or related genes.
Ronan Curtin, Desmond J. Fitzgerald
openaire   +3 more sources

Antiplatelet Ajanlara Bağlı İntrakraniyal Kanamalarda Profilaktik Platelet Transfüzyonu

, 2016
Acil serviste çok sık karşılaştığımız hastalıklardan bir tanesi hemorajik inme vakalarıdır. Hemorajik inmeler tüm inme vakalarının %10-20’sini oluşturmaktadır ve inmeye bağlı ölümlerin %50’sinden ve inmeye bağlı engelliliğin de %42’sinden sorumludur (1,2)
Erkman Sanrı
core   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source