Results 201 to 210 of about 143,360 (302)

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

P2Y<sub>12</sub> inhibitor pre-treatment in NSTE-ACS: translating trial evidence into UK clinical practice. [PDF]

open access: yesOpen Heart
Hesse K   +16 more
europepmc   +1 more source

Pirtobrutinib in Richter syndrome: Outcomes from the named patient programme in Italy

open access: yes
British Journal of Haematology, EarlyView.
Isacco Ferrarini   +19 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

open access: yesHaemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini   +4 more
wiley   +1 more source

Mechanisms for the in vivo antiplatelet effects of isosorbide dinitrate.

open access: yes, 1988
Mechanisms for the in vivo antiplatelet effects of isosorbide dinitrateDe Caterina R   +3 more
core  

Understanding Contact Risks of Pediatric Physical Activity: Video Analysis to Inform Decisions for Children at Risk of Bleeding Injuries

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Physical activity guidelines for children with inherited or acquired bleeding disorders are largely based on expert opinion rather than objective measures of injury exposure, making evidence‐based participation recommendations challenging.
Lauren Backstein   +10 more
wiley   +1 more source

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