Background Although numerous studies have demonstrated a strong association between blood pressure (BP) and hemorrhagic complications of antithrombotic therapy, there is still a paucity of information regarding the status of BP control in hypertensive ...
Naoyuki Odaguchi +2 more
doaj +1 more source
ObjectiveAntithrombotic therapy in patients with nonvalvular atrial fibrillation (NVAF) concomitant with the acute coronary syndrome (ACS) or underwent percutaneous coronary intervention (PCI) is challenging and has evolved in recent years. However, real-
Ni Suo +6 more
doaj +1 more source
Drug resistance with monitored adherence [PDF]
Drug resistance can be defined as the failure of a drug to exert its expected effect on pharmacological biomarkers and is caused by pharmacogenetic, cellular or clinical factors.
Walter, Philipp Niklaus
core +1 more source
Synthesis and Antiplatelet Activity of 4-Hidroxy-3-Methoxycinnamic Acid
Background: Cinnamic acid and its derivatives have been widely studied for their efficacy because of the pharmacological effect on good health and well being.
Erika Christy Marentek +2 more
doaj +1 more source
Antiplatelet activity should be measured routinely: no [PDF]
Antiplatelet agents such as aspirin, clopidogrel, anddipyridamole are effective in secondary stroke pre-vention with single agents reducing risk by 15 % to 20%1–3; the addition of a second agent (eg, combining aspirin and dipyridamole) doubles this ...
Philip M. W. Bath, Bath, Philip M.W.
core +1 more source
Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Demchuk, A. +8 more
core +1 more source
Impact of anticoagulation and antiplatelet therapy on dialysis catheter fibrin sheath formation [PDF]
PURPOSEFibrin sheaths are a significant cause of dialysis catheter dysfunction. This study aimed to determine the role of anticoagulation, antiplatelet medications, and other factors in delaying fibrin sheath formation.METHODSAn institutional review ...
Forrest B. Linch +5 more
core +1 more source
Drug interactions and hepatotoxicity of clopidogrel [PDF]
Clopidogrel (Plavix¨) is an antiplatelet drug, which is clinically used in combination with aspirin to reduce cardiovascular events in patients undergoing percutaneous coronary intervention or in patients suffering from acute coronary syndromes ...
Zahno, Anja-Christina
core +1 more source
Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention [PDF]
Complex percutaneous coronary intervention (PCI) patients are a high-risk population for ischemic complications. Antiplatelet therapy in such patients remains controversial, as the beneficial effects of more potent agents use or prolonged dual ...
Dimitrios Alexopoulos +2 more
core +1 more source
Bleeding Risk of Cerebral Cavernous Malformations in Patients on Statin and Antiplatelet Medication: A Cohort Study. [PDF]
BACKGROUND Statin medication has been identified as a potential therapeutic target for stabilizing cerebral cavernous malformations (CCMs). Although increasing evidence suggests that antiplatelet medication decreases the risk of CCM hemorrhage, data ...
Mattia Branca +11 more
core +1 more source

