Results 101 to 110 of about 159,806 (339)
Hemobilia from biliary angiodysplasia diagnosed with cholangioscopy [PDF]
, 2016 Biliary angiodysplasia is extremely rare. Our background search revealed only a few case reports in the English literature. We present a case of angiodysplasia of the proximal common bile duct in a patient with subacute upper gastrointestinal bleeding ...
Foong, Kap Sum +3 more
core +2 more sources
Pharmacogenetics of Antiplatelet Drugs [PDF]
The Scientific World JOURNAL, 2002 Pharmacogenetics refers to the genetic factors that influence the response to a drug, often involving genetic variations in drug metabolizing enzymes. The pharmacogenetics of antiplatelet agents is in its infancy and largely reflects variations in drug targets or related genes.
Ronan Curtin, Desmond J. Fitzgerald
openaire +3 more sources
Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Angewandte Chemie International Edition, EarlyView.Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Antiplatelet activity of deferiprone through cyclooxygenase-1 inhibition
Platelets, 2020 Thalassemia patients are susceptible to both iron overload and thromboembolism. Deferiprone is an iron chelator that shows an antiplatelet activity and thus may alleviate platelet hyperactivation in thalassemia.
Ngan Thi Tran +4 more
doaj +1 more source
Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke:Pooled analysis of randomized trials [PDF]
, 2015 Background and Purpose: Lacunar stroke accounts for ≈25% of ischemic stroke, but optimal antiplatelet regimen to prevent stroke recurrence remains unclear.
Benavente, Oscar R. +5 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla +13 more
wiley +1 more source
ABC of arterial and venous disease. Secondary prevention of transient ischaemic attack and stroke [PDF]
, 2000 No abstract ...
Bath, P.M.W., Lees, K.R., Naylor, A.R.
core +1 more source
Clinical pharmacology and therapy, 2020 Genotyping for CYP2C19 no function alleles to guide antiplatelet therapy after percutaneous coronary intervention (PCI) improves clinical outcomes. Although results for the increased function CYP2C19*17 allele are also reported, its clinical relevance in
Craig R. Lee +23 more
semanticscholar +1 more source
British Journal of Clinical Pharmacology, EarlyView.Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo +22 more
wiley +1 more source
Correlation between prescribing quality and pharmaceutical costs in English primary care: national cross-sectional analysis [PDF]
, 2011 Background Both pharmaceutical costs and quality-indicator performance vary substantially between general practices, but little is known about the relationship between prescribing costs and quality Aim To measure the association between prescribing ...
Allsup +8 more
core +1 more source