Results 131 to 140 of about 249,854 (357)
British Journal of Clinical Pharmacology, EarlyView.Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi +3 more
wiley +1 more source
One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]
, 2016 BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W. +20 more
core +2 more sources
BMEMat, EarlyView.A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen +9 more
wiley +1 more source
Selective COX-2 inhibitors and risk of myocardial infarction [PDF]
, 2005 Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids.
Klauss, V. +3 more
core +1 more source
Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy
BMEMat, EarlyView.This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang +5 more
wiley +1 more source
The role of green tea intake in thromboprophylaxis of venous thromboembolism in patients with cancer
Frontiers in NutritionBackgroundGreen tea intake has been reported to improve the clinical outcomes of patients with cardiovascular diseases or cancer. It may have a certain role in the development of venous thromboembolism (VTE) among cancer patients. The current study aimed
Qihuan Yao +10 more
doaj +1 more source
Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]
, 2018 The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky +3 more
core +1 more source
Outcomes of Left Atrial Appendage Occlusion in Heart Failure With Reduced Ejection Fraction
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Patients with heart failure with reduced ejection fraction (HFrEF) were excluded from major trials of left atrial appendage occlusion (LAAO). Aim The objective of this study was to describe this population and evaluate outcomes after LAAO in patients with and without HFrEF.
Aamer Ubaid +4 more
wiley +1 more source