Results 311 to 320 of about 159,806 (339)
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Antiplatelet activity of tetramethylpyrazine
Thrombosis Research, 1994Tetramethylpyrazine (TMPZ) is an active ingredient of a Chinese herbal medicine. We have previously shown that TMPZ possesses antithrombotic activity in rat thrombotic models. Inhibition of platelet aggregation and promotion of disaggregation contributed to the antithrombotic activity of TMPZ.
S Y, Liu, D M, Sylvester
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Antiplatelet therapy and exodontia
The Journal of the American Dental Association, 2015This is a review of the management considerations regarding exodontia for patients taking antithrombotic medications that affect platelet function or aggregation.The authors reviewed the literature, focusing on the indications and mechanisms of antiplatelet therapy and the perioperative management of patients taking these agents who require exodontia ...
Willem H, Schreuder, Zachary S, Peacock
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Current concepts and novel targets for antiplatelet therapy
Nature Reviews Cardiology, 2023M. Gawaz, T. Geisler, O. Borst
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Antiplatelet Therapy in Diabetes
Endocrinology and Metabolism Clinics of North America, 2018Cardiovascular disease (CVD) is a significant cause of morbidity and mortality among patients with diabetes mellitus (DM). Increased platelet reactivity among patients with DM contributes to disproportionately high levels of atherothrombotic CVD. Consequently, there has been tremendous interest in exploring the role of antiplatelet therapies in DM to ...
Arjun, Majithia, Deepak L, Bhatt
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Aspirin as an Antiplatelet Agent
Archives of Internal Medicine, 1980To the Editor. —There have been many studies relating the effect of aspirin prophylaxis on thromboembolisms. 1,2 Evaluation of the clinical data presented in them indicates that thromboembolic disease developed more rarely in men than in women under the identical dosage of aspirin given for prophylaxis against thromboembolism after hip surgery and ...
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Aspirin as an Antiplatelet Drug
New England Journal of Medicine, 1994The past 10 years have witnessed major changes in our understanding of the pathophysiologic mechanisms underlying vascular occlusion1,2 and considerable progress in the clinical assessment of aspirin and other antiplatelet agents3–5. The purpose of this review is to describe a rational basis for antithrombotic prophylaxis and treatment with aspirin ...
Alastair J.J. Wood, Carlo Patrono
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Antiplatelet effect of capsaicin
Thrombosis Research, 1984Capsaicin was found to be a potent inhibitor of platelet aggregation and release reaction. It inhibited the aggregation of rat platelet induced by collagen and thrombin, but only slightly reduced those of AA and A23187. The IC50 on collagen-induced platelet aggregation was about 85 micrograms/ml.
J P, Wang, M F, Hsu, C M, Teng
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Arteriosclerosis, Thrombosis and Vascular Biology, 2019
Current guidelines recommend dual antiplatelet therapy—a P2Y12 inhibitor (clopidogrel, prasugrel, or ticagrelor) and aspirin—for patients undergoing percutaneous coronary intervention. Although clopidogrel is the most commonly prescribed P2Y12 inhibitor,
Melissa D. Klein +3 more
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Current guidelines recommend dual antiplatelet therapy—a P2Y12 inhibitor (clopidogrel, prasugrel, or ticagrelor) and aspirin—for patients undergoing percutaneous coronary intervention. Although clopidogrel is the most commonly prescribed P2Y12 inhibitor,
Melissa D. Klein +3 more
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Exodontia and Antiplatelet Therapy
Journal of Oral and Maxillofacial Surgery, 2008The fear of excessive bleeding often prompts the physician to stop long-term, low-dose antiplatelet therapy before any surgical procedure. This may put the patient at risk of an adverse thromboembolic event. We undertook an assessment of the incidence of prolonged postoperative bleeding after dental extractions among patients on uninterrupted ...
Balasubramanian, Krishnan +2 more
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Highlights: Introduction Goals of Treatment Antiplatelet Therapy Combination Therapy Monographs ...
Megan Willson, Kimberly C. McKeirnan
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Megan Willson, Kimberly C. McKeirnan
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