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Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo +22 more
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Efficacy and Safety of Drug and Device Strategies for Stroke Prevention in Atrial Fibrillation After Intracranial Hemorrhage: A Bayesian Network Meta-Analysis. [PDF]
Qi F +8 more
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Prior Dual Antiplatelet Therapy and Mortality After Intracerebral Hemorrhage: A Danish Nationwide Cohort Study. [PDF]
Ovesen C +7 more
europepmc +1 more source
Impact of CYP2C19 point-of-care testing on the clinical outcome in patients receiving personalized clopidogrel therapy: systemic review and meta-analysis. [PDF]
Mohammed S +8 more
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Extending Dual Antiplatelet Therapy Beyond 3 Months in Acute Ischemic Stroke Due to Large-Artery Atherosclerosis. [PDF]
Lee M +35 more
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Circulation, 2023
Antiplatelet therapy is the mainstay of pharmacologic treatment to prevent thrombotic or ischemic events in patients with coronary artery disease treated with percutaneous coronary intervention and those treated medically for an acute coronary syndrome ...
D. Capodanno +40 more
semanticscholar +1 more source
Antiplatelet therapy is the mainstay of pharmacologic treatment to prevent thrombotic or ischemic events in patients with coronary artery disease treated with percutaneous coronary intervention and those treated medically for an acute coronary syndrome ...
D. Capodanno +40 more
semanticscholar +1 more source

