SGLT2i use and fracture risk compared with DPP4i in patients with T2DM
ABSTRACT Introduction The association between sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) use and fracture risk remains inconclusive. Most previous studies have focused on treatment‐naïve patients, despite many patients in routine clinical practice initiating SGLT2i therapy after prior dipeptidyl peptidase‐4 inhibitor (DPP4i) use.
Sung‐Yen Lin +5 more
wiley +1 more source
Antithrombotic Therapy after Structural Heart Disease Intervention. [PDF]
Hara H.
europepmc +1 more source
Early Antiplatelet Therapy in Upper Gastrointestinal Bleeding with Coronary Artery Disease: A Landmark Analysis of MIMIC-IV and eICU-CRD Databases. [PDF]
Zhong X.
europepmc +1 more source
Dual Antiplatelet Therapy and Very Early Neurological Deterioration after Non-Cardioembolic Stroke According to Stroke Etiology. [PDF]
Pereppadan RS +8 more
europepmc +1 more source
ABSTRACT Background Pharmacologic therapies to prevent decompensation in cirrhosis remain limited. Aim To evaluate the association between aspirin use and cirrhosis‐related outcomes and mortality. Methods This retrospective cohort study utilized deidentified electronic health records from a global federated network (January 2013–July 2025). Adults with
Shahem Abbarh +6 more
wiley +1 more source
Role of light transmission aggregometry in predicting diffusion-weighted imaging lesions after stent-assisted coil embolization for intracranial aneurysms: a retrospective propensity score-matched study. [PDF]
Kan I +8 more
europepmc +1 more source
Hip Fracture Risk of Lemborexant and Suvorexant in Comparison With Z‐Drugs: A Target Trial Emulation
ABSTRACT Background Lemborexant and suvorexant are widely used dual orexin receptor antagonists (DORAs) for the pharmacological treatment of insomnia. Although they are generally considered safer than benzodiazepine receptor agonists (Z‐drugs) regarding adverse events including hip fractures, evidence from direct comparisons remains limited. This study
Yuichiro Matsuo +5 more
wiley +1 more source
The OCEANIC trial journey: from failure to breakthrough? [PDF]
Caso V, Ten Cate H, van Gelder IC.
europepmc +1 more source

