Results 91 to 100 of about 116,219 (214)

Residual Shunt at 6 Months Follow‐up After Percutaneous Patent Foramen Ovale Closure in CAHAL: A Comparison of Occlutech and Amplatzer

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Residual shunt is a known complication in percutaneous patent foramen ovale (PFO) closure, and moderate to large residual shunt has been associated with an increased risk of recurrent stroke. Device‐related factors, such as device size, have been associated with residual shunt, but comparative data per device type are scarce.
Jelle D. Nieuwendijk, Abdelhak el Bouziani, Lars S. Witte, Danielle Robbers‐Visser, Berto J. Bouma, Bart Straver, Ibtihal al Amri, Jonathan M. Coutinho, Ronak Delewi, Robbert J. de Winter, Marcel A. M. Beijk, Frank van der Kley, Maik J. Grundeken   +12 more
wiley   +1 more source

Optimal Antithrombotic Therapy for Peripheral Artery Disease: A Systematic Review and Network Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The optimal antithrombotic regimen for peripheral artery disease, balancing thromboembolic and bleeding risks, remains uncertain. This study aimed to compare the efficacy and safety of antithrombotic regimens in patients with peripheral artery
Yuriko Hiruma, Atsuyuki Watanabe, Tadao Aikawa, Masao Iwagami, Leandro Slipczuk, Jose Wiley, Alexandros Briasoulis, Eric Secemsky, Roger Laham, Toshiki Kuno   +9 more
doaj   +1 more source

Long‐Term Prognostic Value of Angiography‐Derived Quantitative Flow Ratio and Radial Wall Strain in Untreated Intermediate Coronary Stenoses: A Retrospective Cohort Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Quantitative flow ratio (QFR) measures angiography‐derived coronary physiology, whereas radial wall strain (RWS) characterizes cyclic lumen deformation. We investigated their complementary long‐term prognostic information in untreated intermediate coronary stenoses and assessed the internal validity of their combined prediction ...
Yixing Chen, Yanqing Wu, Daqiu Chen, Feng Wu, Xianhua Ye, Tao Ye, Qixiang Song, Shumin Fan, Shunxiang Luo, Shanghua Xu   +9 more
wiley   +1 more source

Inflammatory Pericardial Effusion With Hemorrhagic Conversion in Takotsubo Cardiomyopathy

JACC: Case Reports
Background: Takotsubo cardiomyopathy (TC) is a reversible stress-induced cardiomyopathy that may be triggered by acute neurologic events. Significant pericardial effusions associated with TC are uncommon, and hemorrhagic transformation is rarely reported.
Ameer Odeh, MD, Nausheen Akhter, MD, Gokce Deniz Ardor, MD, Mohammed Ruzieh, MD, MSE   +3 more
doaj   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

A functional antiplatelet nanomotor for tri-modal ablation of acute arterial thrombus

Cell Reports Medicine
Summary: Timely and safe thrombolysis is a priority in the clinical management of acute arterial embolism. However, current drug therapies face the challenge of balancing therapeutic benefits with bleeding risks.
Haonan Wu, Hongyuan Zhang, Shuting Guo, Fu Yao, Yuting Sun, Yuan Sun, Shenwu Zhang, Yuequan Wang, Cong Luo   +8 more
doaj   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho, HoJin Shin, Mehdi Najafzadeh, Brian Claggett, Janinne Ortega‐Montiel, Jun Liu, Julie M. Paik, Narlina F. Lalani, Marie C. Bradley, John Concato, Scott D. Solomon, Orly Vardeny, Elisabetta Patorno   +12 more
wiley   +1 more source

Antithrombotic therapy for hepatic artery thrombosis following liver transplantation: a case report and literature review

Frontiers in Pharmacology
BackgroundHepatic artery thrombosis (HAT) is one of the most severe complications following liver transplantation (LT). Its prevention requires balancing the risks of bleeding and embolism.
Ziwan Guan, Sha Qiu
doaj   +1 more source

Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross‐sectional study

Clinical Pharmacology &Therapeutics, EarlyView.
The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang, Guiling Zhou, Jens H. J. Bos, Eelko Hak, Talitha Feenstra, Frank Klont   +5 more
wiley   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source