Results 141 to 150 of about 116,219 (214)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Urolithin A has antiplatelet effects in contrast to its glucuronide, urolithin B, and isourolithin A. [PDF]

Front Cardiovasc Med
Soloviova A, Hrubša M, García CJ, Lomozová Z, Tomás-Barberán FA, Mladěnka P.   +5 more
europepmc   +1 more source

Interventional Radiology Society of Australasia Quality Care Guidelines for Renal Tumour Ablation in Australia and New Zealand

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Image‐guided thermal ablation (radiofrequency, cryo‐ and microwave ablation) is a safe and effective primary treatment for small renal mass and localised renal cell carcinoma ≤ 4 cm (T1a) with long‐term cancer‐specific survival rates equivalent to surgical resection (Level A).
Matthew Lukies, William Ormiston, Nicholas Brown, Philip Chan, Ahmad Al‐Hindawi, Radha Popuri, Brendan Buckley   +6 more
wiley   +1 more source

Long-term outcomes of antithrombotic treatment for retinal vein occlusion. [PDF]

Res Pract Thromb Haemost
Sacchet D, Lodigiani C, Sacco C, Barco S, Wolf S, Zweifel S, Donadini MP, Librè L, Bertù L, Ageno W.   +9 more
europepmc   +1 more source

Whole‐Body CT Utilisation in Adult Trauma: Guideline Compliance, Incidental Findings, and the Role of Anticoagulation in Low‐Energy Falls at a Regional New Zealand Centre

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Whole‐body CT (WBCT) is central to major trauma assessment, but indiscriminate use carries a substantial radiation burden. The Central Region Trauma Network's Early Radiological Imaging in Major Trauma Guideline (CPG154), adopted at this centre, specifies criteria for WBCT and excludes low‐energy falls from standing height.
Vamsi Thammandra, Jonny Russell
wiley   +1 more source

Linear Accelerator–Based Stereotactic Body Radiotherapy of 36.25 Gy in Five Fractions for Localised Prostate Cancer: A Retrospective Single‐Institution Cohort Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Stereotactic body radiotherapy has become an established treatment option for localised prostate cancer. However, real‐world evidence from routine clinical practice remains limited, particularly in cohorts that include older patients.
Atsuto Katano, Hideomi Yamashita
wiley   +1 more source

Cross‐Sectional Study of the PREValence of Erectile DysfunctIon in the Arteriopathic Population (PREVEDI)

Andrology, EarlyView.
ABSTRACT Background Although the association between erectile dysfunction (ED) and cardiovascular disease is well established, its prevalence in patients with atherosclerosis remains poorly defined. Objectives To evaluate ED prevalence, severity, and associated risk factors (RFs) in patients with atherosclerotic disease.
Luca Farchioni, Andrea Ferri, Nicola Leone, Mattia Migliari, Luigi Alberto Maria Bartolotti, Daniele Santi, Giorgia Spaggiari, Roberto Silingardi, Stefano Gennai   +8 more
wiley   +1 more source

Predicting Device‐Induced Platelet Damage in Assisted Circulation Using a New Biophysical Model and Experimental Validation

Artificial Organs, EarlyView.
Quantitative assessment of a newly proposed CFD‐based biophysical model for predicting device‐induced platelet damage by circulatory assist devices was performed. The new model preserved the relative trends observed previously with the power‐law formulation across a range of clinically relevant pump operating conditions, while demonstrating improved ...
Anik Tarafder, Dong Han, Bartley P. Griffith, Zhongjun J. Wu   +3 more
wiley   +1 more source

Single antiplatelet therapy and tirofiban bridged with surface modified flow diverters for ruptured blood blister-like aneurysms: single center experience and systematic review. [PDF]

J Neurointerv Surg
Chen CC, Chen CT, Yeap MC, Chien SC, Hsieh PC, Wu YM, Hong KT.   +6 more
europepmc   +1 more source

Continuous‐Flow Left Ventricular Assist Devices in Biventricular Configuration: A Systematic Review and Comparative Meta‐Analysis of HeartMate 3 and HeartWare Biventricular Assist Devices

Artificial Organs, EarlyView.
HeartWare‐BiVAD was associated with more frequent right ventricular cannulation, whereas HM3‐BiVAD demonstrated a trend toward improved survival despite a more severe preimplant clinical profile, suggesting a potential device‐related advantage of HM3 in biventricular support.
Daler Rahimov, Aryana J. Jones, Chidi Ome Irondi, Yookang Nam, Faizaan Siddique, Eugene Storozynsky, Gregory T. Gibson, Susan M. Joseph, Keshava Rajagopal, Charles W. Hoopes, Vakhtang Tchantchaleishvili   +10 more
wiley   +1 more source