Results 61 to 70 of about 249,854 (357)

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

open access: yes, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy   +4 more
core   +3 more sources

Congenital anomaly of coronary artery: absence of left circumflex artery

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2019
The prevalence of congenital coronary artery anomalies is approximately 1% in the general population. They are a common cause of sudden death in younger persons. Congenital absence of the left circumflex artery is usually a benign condition but can cause
Muhammad Shabbir Rawala   +5 more
doaj   +1 more source

Treatment inequity in antiplatelet therapy for ischaemic heart disease in patients with advanced chronic kidney disease: releasing the evidence vacuum

open access: yesPlatelets, 2023
Chronic kidney disease (CKD) is a global health problem and an independent risk factor for cardiovascular morbidity and mortality. Despite evidence-based therapies significantly improving cardiovascular mortality outcomes in the general population and ...
Frances L. Varian   +3 more
doaj   +1 more source

Platelet-collagen adhesion: evidence for participation of antigenically distinct entities. [PDF]

open access: yes, 1984
Univalent antibody fragments prepared from a rabbit antiserum raised against whole human platelets completely inhibited adhesion of platelets to immobilized trimeric collagen in a defined, Mg2+-dependent, adhesion assay.
Barondes, SH, Shadle, PJ
core   +2 more sources

The Emerging Role of Platelets in the Formation of the Micrometastatic Niche: Current Evidence and Future Perspectives

open access: yesFrontiers in Oncology, 2020
Accumulating evidence suggests that platelets play a key role in cancer metastatic dissemination through their multilevel interaction with tumor cells. Most crucial is the contribution of platelets to the formation and expansion of the early metastatic ...
Stavros Gkolfinopoulos   +4 more
doaj   +1 more source

Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases

open access: yesPlatelets, 2021
Antiplatelet medications comprise the cornerstone of treatment for diseases that involve arterial thrombosis, including acute coronary syndromes (ACS), stroke and peripheral arterial disease.
Maan H. Harbi   +4 more
doaj   +1 more source

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

open access: yes, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O.   +4 more
core   +1 more source

More, More, More: Reducing Thrombosis in Acute Coronary Syndromes Beyond Dual Antiplatelet Therapy-Current Data and Future Directions. [PDF]

open access: yes, 2018
© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.Common to the pathogenesis of acute coronary syndromes (ACS) is the formation of arterial thrombus, which results from platelet activation and triggering of the ...
Farag M   +6 more
core   +3 more sources

Embolic strokes of undetermined source: prevalence and patient features in the ESUS Global Registry [PDF]

open access: yes, 2016
Background: Recent evidence supports that most non-lacunar cryptogenic strokes are embolic. Accordingly, these strokes have been designated as embolic strokes of undetermined source (ESUS).
Ameriso, Sebastian F   +27 more
core   +5 more sources

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

open access: yesMolecules, 2014
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1–5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo.
Rafael Consolin Chelucci   +6 more
doaj   +1 more source

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