Results 261 to 270 of about 181,112 (317)

Atypical antipsychotic profiles of dopamine D4 receptor antagonist, (R) - (+) - 2-amino - 4 -(4-fluoro-phenyl)-5-[1-[4-(4-fluorophenyl)-4-oxobutyl] pyrrolidin-3-ylJthiazole (NRA0045) in Rats

, 1997
Shinichi Ogawa, Shigeru Okuyama, Yoshiko Suzuki, Shigeyuki Chaki, Toshihito Kumagai, Atsuro Nakazato, Yoko Ikeda, Masashi Nagamine, Makoto Gotoh, Masanori Yoshida, Kazuyuki Tomisawa   +10 more
openalex   +1 more source

The Impact of Metformin on Weight and Waist Circumference in Patients Treated With Clozapine: A One‐Year Retrospective Cohort Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Metformin shows potential in combating clozapine‐induced weight gain (CIWG). However, current evidence for its use remains limited. Through an audit we determined the prevalence of metformin use among clozapine‐treated patients and its impact on weight and waist circumference (WC).
Bee Leng Per, Susan Loeser, Suzanne Edwards, Wen Siew Lee, Lisa R. Wilton, Scott Richard Clark   +5 more
wiley   +1 more source

The mechanism of action of clozapine. [PDF]

J Psychopharmacol
Morrison PD, Jauhar S, Young AH.
europepmc   +1 more source

Behavioral pharmacological studies of OPC-14597, a novel antipsychotic drug : Comparison with OPC-4392, clozapine and haloperidol.

, 1996
Tetsuro Kikuchi, Yasufumi Uwahodo, Katsura Tottori, Masami Nakai, Tsuyoshi Hirose, Yasuo Oshiro, Seiji Morita   +6 more
openalex   +1 more source

Interrelationships of Changes in Outcome Domains in Patients With Schizophrenia Spectrum Disorders: A Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Patients with schizophrenia spectrum disorders (SSD) improve in several outcome domains over the course of illness, but to different degrees. In this meta‐analysis, we investigated whether longitudinal changes in different outcome domains are associated with each other and which factors moderate these changes over time.
Lars de Winter, Auke Jelsma, Jentien M. Vermeulen, Astrid Vellinga, Jaap van Weeghel, Ilanit Hasson‐Ohayon, Cornelis L. Mulder, Nynke Boonstra, Wim Veling, Lieuwe de Haan   +9 more
wiley   +1 more source

Formulating Cognitive Functioning to Guide Personalised Treatment for People Diagnosed With Mental Disorders

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Objective and subjective cognitive impairment are highly prevalent in mental disorders and transdiagnostic phenomena. Cognitive impairment is associated with poorer functional outcomes and therefore requires treatment, but little guidance is available for clinicians.
Kelly Allott, Shayden Bryce, Katie Douglas, Alexandra Stainton, Stephen J. Wood, Christopher R. Bowie   +5 more
wiley   +1 more source

Real-World Effectiveness of Long-Acting Injectable and Oral Antipsychotic Agents in US Medicare Patients with Schizophrenia. [PDF]

Adv Ther
Li P, Geng Z, Benson C, Patel C, Doshi JA.   +4 more
europepmc   +1 more source

Designing Naturalistic Prospective Studies of Economic and Effectiveness Outcomes Associated with Novel Antipsychotic Therapies

, 2000
Sandra L. Tunis, Bryan M. Johnstone, Bruce J. Kinon, Beth Barber, Robert A. Browne   +4 more
openalex   +1 more source

Drug Interaction With Advanced Therapies in Inflammatory Bowel Diseases: A Blind Spot to Tackle

United European Gastroenterology Journal, EarlyView.
Nathan Grellier, Julien Kirchgesner
wiley   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source