Results 231 to 240 of about 3,281,120 (365)

Deprescribing Benzodiazepine Receptor Agonists in Older Adults and People With Cognitive Impairment: A Systematic Review

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Benzodiazepine receptor agonists (BZRAs) (benzodiazepines and z‐drugs) may provide limited benefits in the management of insomnia when used short‐term. However, they increase the risk of harms including falls, fractures, hospitalizations, and cognitive impairment. Deprescribing (cessation) of BZRAs may be beneficial for older adults
Aisling M. McEvoy, Aili V. Langford, Shin J. Liau, Darshna Goordeen, Emily Reeve, Justin P. Turner   +5 more
wiley   +1 more source

Central Blood Pressure and Augmentation Index in Older Adults With Intellectual Disabilities

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Older adults with intellectual disabilities are at a higher cardiovascular risk than their peers in the general population. Investigating central blood pressure and augmentation index is necessary to better understand the risk of cardiovascular disease, to better identify those individuals at risk and to potentially change ...
T. I. M. Hilgenkamp, A. Oppewal, M. N. Bohmer, A. Paul, C. Ryan, E. Burke, M. McCarron, P. McCallion, D. A. M. Maes‐Festen, F. O'Brien   +9 more
wiley   +1 more source

Cardiovascular Disease Incidence and Risk Factors in Older Adults With Intellectual Disabilities: Results of the Healthy Ageing and Intellectual Disabilities Study

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Previous research has shown that older adults with intellectual disabilities are at increased risk of cardiovascular diseases (CVD). However, longitudinal studies investigating the actual incidence of CVD and its associated risk factors in this population are limited. Such research is essential for optimising healthcare delivery and
Marleen J. de Leeuw, Mylène N. Böhmer, Patrick J. E. Bindels, Dederieke A. M. Maes‐Festen, Alyt Oppewal   +4 more
wiley   +1 more source

Changes in Health Risks, Daily Activities and Antipsychotic Use After Humanitude Care for People With Dementia: A Retrospective Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim This study examined changes in health risk, daily activities and antipsychotic use after receiving Humanitude care for people with dementia. Design Retrospective study design. Methods A total of 67 people with dementia were admitted to two municipal nursing hospitals and were receiving Humanitude care.
Sungjun Kim, Jiyoung Kim, SungWoo Chung, Ju Young Sim   +3 more
wiley   +1 more source

FTBMT, a Novel and Selective GPR52 Agonist, Demonstrates Antipsychotic-Like and Procognitive Effects in Rodents, Revealing a Potential Therapeutic Agent for Schizophrenia

, 2017
Keiji Nishiyama, Hirobumi Suzuki, Toshiya Harasawa, Noriko Suzuki, Emi Kurimoto, Takayuki Kawai, Minoru Maruyama, Hidetoshi Komatsu, Kensuke Sakuma, Yūji Shimizu, Masato Shimojo   +10 more
openalex   +1 more source

Renal Toxicity of a Nondopaminergic Antipsychotic Agent, Trimethyl Imidazopyrazolopyrimidine, in Rats [PDF]

, 1994
Grace E. Macallum, Mudher Albassam
openalex   +1 more source

Regular Medications Administered to Older Adults in Aged Care Facilities: A Retrospective Descriptive Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim(s) To explore which regularly prescribed medications are most commonly administered to older adults in aged care facilities in Australia, by whom and when, and to identify the prevalence of polypharmacy in this population group. Design Retrospective descriptive study.
Stephanie M. Garratt, Maneesh Prasad, Kelly Ottosen, Elizabeth Manias   +3 more
wiley   +1 more source

A case of serotonin syndrome following the reintroduction of aripiprazole after dextromethorphan overdose. [PDF]

PCN Rep
Abstract Background Serotonin syndrome is a potentially life‐threatening condition that arises from excessive serotonergic activity. Dextromethorphan (DXM), commonly used as a non‐prescription antitussive, can induce serotonin syndrome when taken in high doses or in combination with other serotonergic agents.
Saito N, Noguchi N, Toida M, Miyauchi M, Asami T.   +4 more
europepmc   +2 more sources

Use of dipeptidyl peptidase‐4 inhibitors is associated with lower risk of severe renal outcomes in pre‐dialysis patients with Type 2 diabetes

Journal of Internal Medicine, EarlyView.
Abstract Objectives Patients with diabetes and Stage 5 chronic kidney disease (CKD) not on dialysis are susceptible to renal replacement therapy and severe complications. Among limited antidiabetic options in this vulnerable population, dipeptidyl peptidase‐4 (DPP‐4) inhibitors (DPP‐4i) are widely used; however, supporting evidence is scant.
Tung‐Ying Hung, Tzu‐Chieh Lin, Ying‐Jay Liou, Tzu‐Han Lin, Yu‐Juei Hsu, Liang‐Yu Lin, Meng‐Ting Wang   +6 more
wiley   +1 more source

Impact of Early Antipsychotic Prescription Choice on Weight Gain in the First 5 Years of Psychotic Illness: a Retrospective Cohort Study. [PDF]

Neurol Ther
Heald A, Tilston G, Warner-Levy JJ, Wilkins L, Williams R, Pillinger T, Deakin W, Longson D, Hassan L, Dalton C, Reynolds GP, Firth J.   +11 more
europepmc   +1 more source