Results 251 to 260 of about 3,371,263 (384)

3[4-[1-(6-Fluorobenzo[b]thiophen-3-yl)-4-piperazinyl]butyl]-2,5,5-trimethyl-4-thiazolidinone: a new atypical antipsychotic agent for the treatment of schizophrenia

open access: green, 1992
Nicholas J. Hrib   +8 more
openalex   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan   +6 more
wiley   +1 more source

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review

open access: yesEuropean Eating Disorders Review, Volume 34, Issue 1, Page 55-70, January 2026.
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes   +3 more
wiley   +1 more source

Repurposing medications to prevent psychosis. [PDF]

open access: yesNpj Ment Health Res
Cohen BM   +4 more
europepmc   +1 more source

Food Addiction Is Strongly Associated With Psychopathology and Reduced Psychological Well‐Being Among Adults Irrespective of BMI

open access: yesEuropean Eating Disorders Review, Volume 34, Issue 1, Page 79-91, January 2026.
ABSTRACT Background and Aims Food addiction has been linked to psychopathology and reduced psychological well‐being. Here, we investigated whether these associations are mainly driven by food addiction itself or mediated via an increase in BMI. Methods Data stem from a nationwide survey from Denmark (n = 1474 participants).
Christina Horsager   +4 more
wiley   +1 more source

Anxiolytic Medication Use in Low‐ Middle‐ and High‐Income Countries: A World Mental Health Surveys Report

open access: yesHuman Psychopharmacology: Clinical and Experimental, Volume 41, Issue 1, January 2026.
ABSTRACT Background Anxiolytic medications, particularly benzodiazepines, are widely prescribed, giving impetus to long‐standing debates about how often these agents should be employed in clinical practice. There are, however, few cross‐country studies of the pharmacoepidemiology of these agents. We report on the frequency of anxiolytic medication use,
Dan J. Stein   +31 more
wiley   +1 more source

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