Results 281 to 290 of about 3,281,120 (365)

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

The treatment characteristics of oral antipsychotics in treatment of adolescents with schizophrenia in China. [PDF]

BMC Psychiatry
Wang H, Zhang Y, Wu T, Dong S, Chi R, Jiang K, Qiu H, Dong W, Si T.   +8 more
europepmc   +1 more source

Toxicological analyses of the bone matrix: Successes and challenges

Archaeometry, Volume 67, Issue 4, Page 1001-1021, August 2025.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano, Lucie Biehler‐Gomez, Cristina Cattaneo, Domenico Di Candia   +3 more
wiley   +1 more source

Steroid-responsive autoimmune psychosis with cerebrospinal fluid-restricted oligoclonal bands and positive tissue-based assay findings: a case series of three patients. [PDF]

BMC Psychiatry
Luo Y, Sun H, Fan J, Zhang X, He Y.
europepmc   +1 more source

Use of Potentially Inappropriate Medications Identified by STOPPFrail Among Danish Care Home Residents: A Nationwide Drug Utilisation Study

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
ABSTRACT Care home residents represent a frail population with limited life expectancy and are often prescribed multiple medications. As therapeutic goals shift in this population, certain treatments may become inappropriate. This study aims to describe potentially inappropriate medication use among Danish care home residents using the Screening Tool ...
Katrine Mose, Carina Lundby, Martin Thomsen Ernst, Jesper Ryg, Anton Pottegård, Lotte Rasmussen   +5 more
wiley   +1 more source

Halved Dose of Antipsychotics Versus High-Dose Antipsychotic Therapy for Relapse in Patients with Schizophrenia Receiving High-Dose Antipsychotic Therapy: A Randomized Single-Blind Trial. [PDF]

Int J Mol Sci
Ataniya R, Koike T, Inamoto A.
europepmc   +1 more source

Editorial: Drug repurposing for cancer treatment: current and future directions. [PDF]

Front Oncol
Lampros M, Vlachos N, Lianos GD, Bali C, Alexiou GA.   +4 more
europepmc   +1 more source

Roluperidone monotherapy, a treatment for negative symptoms in schizophrenia. [PDF]

Int J Neuropsychopharmacol
Davidson M, Noel N, Schmitt F, Luthringer R.   +3 more
europepmc   +1 more source

Synthesis of 2-(3-aminopropyl)benzopyrans as potential antipsychotic agents targeting D2/D3 and 5-HT2A receptors

Álvaro Bernabeu-Sanchis, María José Varela, Ainhoa García, Carlos Villarroel-Vicente, Laura Vila, Marı́a Isabel Loza, José Brea, Diego Cortés, Nuria Cabedo   +8 more
openalex   +1 more source

Repurposed Antipsychotics as Potential Anticancer Agents: Clozapine Efficacy and Dopaminergic Pathways in Neuroblastoma and Glioblastoma

Catarina Moura, Maria João Gouveia, Nuno Vale   +2 more
openalex   +1 more source