Results 311 to 320 of about 3,281,120 (365)
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Risk of cerebrovascular adverse events in older adults using antipsychotic agents: a propensity-matched retrospective cohort study.

Journal of Clinical Psychiatry, 2010
OBJECTIVE To compare the risk of cerebrovascular adverse events with second-generation antipsychotic users versus those taking first-generation antipsychotics in community-dwelling older adults.
S. Mehta   +3 more
semanticscholar   +1 more source

The effect of metformin on anthropometrics and insulin resistance in patients receiving atypical antipsychotic agents: a meta-analysis.

Journal of Clinical Psychiatry, 2010
CONTEXT In the Clinical Antipsychotic Trials of Intervention Effectiveness, atypical antipsychotics (AAPs) were found to be associated with weight gain and impairment of glucose metabolism.
M. Ehret   +3 more
semanticscholar   +1 more source

Clozapine

New England Journal of Medicine, 1991
This review considers the discovery of clozapine; its chemistry, pharmacologic activities, metabolism, and pharmacokinetics; evidence of its efficacy; and its side effects and appropriate clinical ...
John A. Oates   +3 more
openaire   +3 more sources

Antipsychotic to anticancer agent?

Nature Reviews Cancer, 2012
A new study shows that a clinically approved drug might selectively target cancer stem cells for differentiation.
openaire   +5 more sources

A long-term trial of the effectiveness and safety of atypical antipsychotic agents in augmenting SSRI-refractory obsessive-compulsive disorder.

Journal of Clinical Psychiatry, 2009
OBJECTIVE Although atypical antipsychotic agents have been found effective in the augmentation of serotonin reuptake inhibitors (SRIs) for treatment-resistant obsessive-compulsive disorder (OCD) in short-term trials, there are few data on the ...
H. Matsunaga   +5 more
semanticscholar   +1 more source

Effect of prior authorization of second-generation antipsychotic agents on pharmacy utilization and reimbursements.

Psychiatric Services, 2008
OBJECTIVE Medicaid expenditures for antipsychotic medications have risen rapidly, from under $1.0 billion in 1995 to over $5.5 billion in 2005. In response, at least ten states have implemented prior-authorization programs that restrict access to ...
M. Law, D. Ross-Degnan, S. Soumerai
semanticscholar   +1 more source

Utilization and costs of antipsychotic agents: a Canadian population-based study, 1996-2006.

Psychiatric Services, 2008
OBJECTIVE This study evaluated the prescribing patterns and costs for antipsychotic agents in the population of the Canadian province of Manitoba over the past decade.
S. Alessi-Severini   +5 more
semanticscholar   +1 more source

Toxicology of Antipsychotic Agents

1980
The introduction of chlorpromazine and reserpine for psychiatric use has been followed by a steady increase in the number of psychotropic agents. In the development of new compounds, there have been many attempts to improve the therapeutic indices and to vary the profile of pharmacodynamic activity in accordance with clinical requirements.
F. Leuschner, R. Hempel, W. Neumann
openaire   +2 more sources

Atypical antipsychotic agents: A critical review

American Journal of Health-System Pharmacy, 2000
The pharmacology, efficacy, and adverse effects of atypical antipsychotic agents when used to treat schizophrenia and other disorders are reviewed. Atypical antipsychotic agents were developed in response to problems with typical agents, including lack of efficacy in some patients, lack of improvement in negative symptoms, and troublesome adverse ...
Jodi A. Worrel   +3 more
openaire   +3 more sources

Prevalence and predictors of lipid and glucose monitoring in commercially insured patients treated with second-generation antipsychotic agents.

American Journal of Psychiatry, 2009
OBJECTIVE The authors sought to quantify plasma lipid and glucose testing rates in patients receiving second-generation antipsychotics before and after guidelines recommending testing were issued in February 2004 by the American Diabetes Association (ADA)
D. Haupt   +5 more
semanticscholar   +1 more source

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