Results 71 to 80 of about 100,926 (300)

Efficacy of atypical antipsychotics in schizophrenia patients: effects of 5-HTR SNPs

open access: yesAnnals of General Psychiatry
The 5-hydroxytryptamine receptor (5-HTR) is a key protein responsible for the effects of 5-hydroxytryptamine (5-HT) and an important target for many antipsychotics.
Keying Liu   +8 more
doaj   +1 more source

Mechanisms of development of antipsychotic-induced metabolic disorders: pharmacogenetic aspect

open access: yesБюллетень сибирской медицины, 2018
Antipsychotics are the main drug group in the treatment of disorders of the schizophrenic spectrum. At the same time, this drug group requires long-term use, has a narrow therapeutic breadth and a large spectrum and high severity of undesirable drug ...
R. F. Nasyrova   +4 more
doaj   +1 more source

The impact of pharmacogenetic‐informed care on medication adherence and psychological factors associated with adherence: A narrative review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway   +2 more
wiley   +1 more source

Interventions to Manage Weight Gain for Pediatric Population on Antipsychotics: A Systematic Review [poster]

open access: yes, 2022
School of Nursing CapstonesThis article systemically reviews studies that present interventions related to pharmacological and non-pharmacological treatment for the weight management and reduction of pediatric patients prescribed antipsychotics.
Gaytan, Claudia
core   +1 more source

Association of typical and atypical antipsychotics with mortality in older adults with schizophrenia: a 5-year multicenter prospective study

open access: yesBrazilian Journal of Psychiatry
Objective: Due to the uncertainty whether atypical and typical antipsychotics have a stronger association with mortality among older people with schizophrenia, we examined the rates and causes of mortality in older adults with schizophrenia who take ...
Raphaëlle Haddad   +7 more
doaj   +1 more source

The prevalence of metabolic syndrome in patients receiving antipsychotics in Qatar: a cross sectional comparative study

open access: yesBMC Psychiatry, 2018
Background Metabolic abnormalities are common in patients maintained on antipsychotics. These abnormalities increase the risk of cardiovascular diseases and mortality in this population.
Samer Hammoudeh   +14 more
doaj   +1 more source

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling   +8 more
wiley   +1 more source

Attitudes of European physicians towards the use of long-acting injectable antipsychotics

open access: yesBMC Psychiatry, 2020
Background Prescription rates for long-acting injectable (LAI) antipsychotic formulations remain relatively low in Europe despite improved adherence over alternative oral antipsychotic treatments.
Maxine X. Patel   +6 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Atypical antipsychotics in bipolar disorder: systematic review of randomised trials

open access: yesBMC Psychiatry, 2007
Background Atypical antipsychotics are increasingly used for treatment of mental illnesses like schizophrenia and bipolar disorder, and considered to have fewer extrapyramidal effects than older antipsychotics.
Moore R Andrew, Derry Sheena
doaj   +1 more source

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