Results 51 to 60 of about 89,416 (210)
Multiple extreme overdose of antipsychotics with minimal side effects: A case report
Key Clinical Message Antipsychotic drug treatment is a commonly used therapeutic strategy in the field of psychiatry. Rational and standardized use of antipsychotics is crucial in clinical practice, and excessive use of antipsychotics may lead to severe ...
Min Yang +3 more
doaj +1 more source
Introduction: Schizophrenia affects approximately 3,810,000 people in the United States and is estimated to cost $155.7 billion. It increases unemployment and poverty, and it is estimated that as much as 25% of the homeless population has schizophrenia ...
Ryan, Brooke
core
Mechanisms of development of antipsychotic-induced metabolic disorders: pharmacogenetic aspect
Antipsychotics are the main drug group in the treatment of disorders of the schizophrenic spectrum. At the same time, this drug group requires long-term use, has a narrow therapeutic breadth and a large spectrum and high severity of undesirable drug ...
R. F. Nasyrova +4 more
doaj +1 more source
Efficacy of memantine for agitation in Alzheimer's dementia: A randomised double-blind placebo controlled trial [PDF]
Agitation in Alzheimer's disease (AD) is common and associated with poor patient life-quality and carer distress. The best evidence-based pharmacological treatments are antipsychotics which have limited benefits with increased morbidity and mortality ...
Crugel Monica +53 more
core +1 more source
Efficacy of atypical antipsychotics in schizophrenia patients: effects of 5-HTR SNPs
The 5-hydroxytryptamine receptor (5-HTR) is a key protein responsible for the effects of 5-hydroxytryptamine (5-HT) and an important target for many antipsychotics.
Keying Liu +8 more
doaj +1 more source
BackgroundCommon atypical antipsychotics include risperidone, paliperidone, olanzapine, lurasidone, quetiapine, clozapine, aripiprazole, ziprasidone, asenapine, brexpiprazole, and cariprazine.
Chao Mu, Li Chen
doaj +1 more source
Background Metabolic abnormalities are common in patients maintained on antipsychotics. These abnormalities increase the risk of cardiovascular diseases and mortality in this population.
Samer Hammoudeh +14 more
doaj +1 more source
Background Psychiatric medications are widely prescribed in the USA. Many antipsychotics cause serum hyperprolactinemia as an adverse side effect; prolactin-Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5) signaling both ...
A. N. Johnston +12 more
doaj +1 more source
Adherence to Antipsychotics in Schizophrenia
Poor adherence to therapy is one of the main obstacles to treatment effectiveness in schizophrenia. It is the main determinant of relapse, hospitalization, symptom persistence, and poor psychosocial functioning and outcome.
Siracusano, A +5 more
core +1 more source

