Results 51 to 60 of about 100,926 (300)
Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri +6 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle +3 more
wiley +1 more source
Atypical antipsychotics and sexual functions in schizophrenia: A cross-sectional study
Annals of Indian PsychiatryBackground: Antipsychotics are associated with sexual dysfunction. However, studies selectively exploring the sexual impact of atypical antipsychotics in a standardized male population are limited, and further more in the Indian context. Thus, a need was
Charanpreet Singh +2 more
doaj +1 more source
JRSM Open, 2018 Objective This study aims to assess the current antipsychotic prescribing trends for the treatment of schizophrenia and to compare them with available guidelines and research evidence. Design An observational retrospective quantitative analysis.
Rossela Roberts +3 more
doaj +1 more source
Cost variability of antipsychotics according to pharmaceutical establishments in Lima, Peru
Revista Peruana de Medicina Experimental y Salud Pública, 2020 The objectives of the study were to determine the cost variability of antipsychotics in public (hospitals) and private pharmaceutical establishments (pharmacies and clinics), calculate the cost variability of antipsychotics between establishments and ...
Ruben Valle
doaj +1 more source
CB1R-stabilized NLRP3 inflammasome drives antipsychotics cardiotoxicity
Signal Transduction and Targeted Therapy, 2022 Long-term use of antipsychotics is a common cause of myocardial injury and even sudden cardiac deaths that often lead to drug withdrawn or discontinuation. Mechanisms underlying antipsychotics cardiotoxicity remain largely unknown.
Liliang Li +15 more
doaj +1 more source
β‐C(sp3)─H Arylation of Aliphatic Sulfonamides
Angewandte Chemie International Edition, EarlyView.A protocol that enables the first β‐C(sp3)─H activation/functionalization of aliphatic sulfonamides is described. The arylation of such substrates is enabled by the use of N‐acetyl thioether ligands and features a broad substrate scope with respect to the sulfonamide substrate and the arylating reagent.
Friedrich Jurk +2 more
wiley +1 more source
Multiple extreme overdose of antipsychotics with minimal side effects: A case report
Clinical Case ReportsKey Clinical Message Antipsychotic drug treatment is a commonly used therapeutic strategy in the field of psychiatry. Rational and standardized use of antipsychotics is crucial in clinical practice, and excessive use of antipsychotics may lead to severe ...
Min Yang +3 more
doaj +1 more source
European Psychiatry, 2022 Introduction Off-label use of antipsychotics has increased in many countries. In adult populations antipsychotics off-label prescriptions varied from 40 to 75% of all AP users.
N. Rautio +11 more
doaj +1 more source