Temporal and spatial transcriptional fingerprints by antipsychotic or propsychotic drugs in mouse brain. [PDF]
Various types of antipsychotics have been developed for the treatment of schizophrenia since the accidental discovery of the antipsychotic activity of chlorpromazine.
Kensuke Sakuma +5 more
doaj +1 more source
Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P +8 more
core +1 more source
Background Medications influencing the risk of fall-related injuries (FRIs) in older adults have been inconsistent in previous guidelines. This study employed case–control design to assess the association between FRIs and medications, and an additional ...
Yu-Seon Jung +5 more
doaj +1 more source
Antipsychotics in child and adolescent patients with major depressive disorder: A retrospective analysis of prescribing patterns [PDF]
Introduction Depression rates in children/adolescents in the United States have increased in the last 10 years. Fluoxetine and escitalopram are the only 2 antidepressants approved for the treatment of major depression disorder (MDD) in children ...
Danielle Dauchot, PharmD +3 more
doaj +1 more source
Medication used in intentional drug overdose in Flanders 2008-2013 [PDF]
Background : Intentional drug overdose is the most common method of self-harm. As psychiatric disorders are very common in self-harm patients, the medication used to treat these disorders can become the means for the self-harm act.
Portzky, Gwendolyn +3 more
core +1 more source
Many pharmacologic agents were investigated for the effect to prevent delirium. We aimed to comprehensively compare the effect of the pharmacological interventions to prevent postoperative delirium.
Sun-Kyung Park +8 more
doaj +1 more source
Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes. [PDF]
IntroductionThere are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral ...
Hsia, Stephanie L +4 more
core +2 more sources
Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core +3 more sources
Forward thinking: where next for delirium prevention research? [PDF]
No abstract ...
Bush +8 more
core +1 more source
Retrospective Study of Midazolam Protocol for Prehospital Behavioral Emergencies [PDF]
Introduction: Agitated patients in the prehospital setting pose challenges for both patient care and emergency medical services (EMS) provider safety. Midazolam is frequently used to control agitation in the emergency department setting; however, limited
Huebinger, Ryan M. +7 more
core +1 more source

