Results 41 to 50 of about 46,487 (292)

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Sertindole in the Management of Schizophrenia

Journal of Central Nervous System Disease, 2011
Nowadays, new schizophrenia treatments are more ambitious than ever, aiming not only to improve psychotic symptoms, but also quality of life and social reinsertion.
Mario F. Juruena, Eduardo Ponde00C9; De Sena, Irismar Reis De Oliveira   +2 more
doaj   +1 more source

Antipsychotic Response in the First Week Predicts Later Efficacy [PDF]

, 2012
Background and Aims: Time of onset of antipsychotic action is still a debated matter. We aimed to replicate and extend previous findings that early response can predict subsequent non-response.
Andrisano, Costanza, Balzarro, Beatrice, Giegling, Ina, Möller, Hans-Jürgen, Porcelli, Stefano, Rujescu, Dan, Schäfer, Martin, Serretti, Alessandro   +7 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]

, 2002
Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B., Dittmann, Sandra, Grunze, Heinz, Walden, Jörg   +3 more
core   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

HOW ASSESS DRUGS IN THE TREATMENT OF ACUTE BIPOLAR MANIA ?

Frontiers in Pharmacology, 2013
Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. Good-quality research available to guide treatment strategies remains insufficient, particularly with regard to manic or hypomanic episodes.
Michel eBourin, Florence eThibaut
doaj   +1 more source

Identifying dopamine supersensitivity through a randomized controlled study of switching to aripiprazole from other antipsychotic agents in patients with schizophrenia

Therapeutic Advances in Psychopharmacology, 2022
Background: Aripiprazole has been reported to worsen psychotic symptoms when switching from other antipsychotics, possibly due to dopamine supersensitivity psychosis.
Chia-Hao Ma, Hung-Yu Chan, Ming H. Hsieh, Chen-Chung Liu, Chih-Min Liu, Hai-Gwo Hwu, Ching-Hua Kuo, Wei J. Chen, Tzung-Jeng Hwang   +8 more
doaj   +1 more source

Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors

Autism Research, EarlyView.
ABSTRACT Cortical thickness (CT) differences between autistic individuals (AI) and neurotypical controls have been consistently reported, yet the neurochemical mechanisms underlying these differences remain insufficiently understood. Neurotransmitter receptor systems exhibit distinct spatial distributions across the cortex and influence synaptic ...
Livio Tarchi, Arne Doose, Julius Hennig, Fabio Bernardoni, Joseph A. King, Tiziana Pisano, Giovanni Castellini, Valdo Ricca, Inge Kamp‐Becker, Stefan Ehrlich   +9 more
wiley   +1 more source

Pharmaceutical-Induced Dyskinesia: A Case Study of Thoracotomy Treated with Amantadine

Case Reports in Clinical Practice
Dyskinesia, marked by involuntary and irregular movements, can result from various pharmaceutical agents. The case presented features a patient undergoing thoracotomy, experiencing dyskinesia, likely attributed to antipsychotics, antiemetics, and ...
Mojtaba Mojtahedzadeh, Atabak Najafi, Farahnaz Hosseinzadeh, Fatemeh Saghafi   +3 more
doaj   +1 more source