Results 131 to 140 of about 37,855 (262)
Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith +5 more
wiley +1 more source
Are inhalers with spacers better than nebulizers for children with asthma? [PDF]
Metered-dose inhalers with a spacer (MDI/S) are as good as, or better than, nebulizers for children with asthma. This is based on numerous randomized controlled trials that compared outcomes such as hospital admission rates, asthma severity scores, and ...
Hsu, Julian T., Parker, Sandi
core
Changing trends in drug overdose mortality in Spain, 2001–2022
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné +6 more
wiley +1 more source
Crimean-congo hemorrhagic fever: Case series from a medical center in golestan province, Northeast of Iran (2004-2006) [PDF]
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed lethal disease, worldwide. Humans are usually infected with CCHF virus through a tick bite or close contact with viral contaminated tissues or with blood of domestic animals or of infected ...
Abbasi, A. +4 more
core
ABSTRACT Relapsed/refractory (R/R) mantle cell lymphoma (MCL) remains a therapeutic challenge, particularly in patients with high‐risk features or prior exposure to Bruton's tyrosine kinase inhibitors (BTKis). The advent of T‐cell–redirecting immunotherapies, including chimeric antigen receptor T‐cell (CAR‐T) therapy and bispecific antibodies (BsAbs ...
Santino Caserta +10 more
wiley +1 more source
Modulation of Immune Cells by Aspirin During Pregnancy
This study explores immune and haematological shifts in high‐risk pregnancies, noting lower haemoglobin and platelet levels linked to maternal risk factors. Th2 cell increases support gestational tolerance, while LDA use correlates with reduced cytotoxic NK CD56dim cells and elevated CD56bright NK and naïve Treg cells, suggesting enhanced immune ...
Ana Luísa Areia +4 more
wiley +1 more source
ACUTE RESPIRATORY INFECTIONS IN CHILDREN — A TACTICS CHOICE
The article is devoted to the most common childhood diseases — acute respiratory infections (ARI). As it is known, the unjustified drug prescriptions and polypragmazy are the most often registered just at ARI.
N.I. Voznesenskaya, T.V. Margieva
doaj +2 more sources
ABSTRACT In February 2023, an 11‐year‐old girl in Cambodia developed severe respiratory symptoms and died of pneumonia and respiratory failure after testing positive for influenza A(H5). Contract tracing and testing identified her father as positive for influenza A(H5). Investigations revealed both were likely exposed to the same sick and dead poultry.
Savuth Chin +14 more
wiley +1 more source
Assessing the pro-poorness of government fiscal policy in Thailand [PDF]
This paper proposes a methodology to assess the pro-poorness of government fiscal policies in view of bringing marginal reforms. A government policy is said to be pro-poor if it benefits the poor proportionally more than the non-poor.
Hyun H. Son
core
Update of the statement on safety of cannabidiol as a novel food
Abstract During the assessment of cannabidiol (CBD) as a novel food, in 2022 the NDA Panel identified significant data gaps. Concerns focused on potential adverse effects on the liver, gastrointestinal tract, endocrine, nervous and reproductive systems.
EFSA Panel on Nutrition +33 more
wiley +1 more source

