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Antipyretic effect of ketoprofen
The Indian Journal of Pediatrics, 2009The aim of this study was to investigate the efficacy and side effect profile of ketoprofen as well as compliance with respect to the taste of the drug and compare these parameters with those of acetaminophen and ibuprofen.A total of 301 patients between 1-14 years of age who applied to emergency rooms of three medical centers with the complaint of ...
Karali, YASİN +7 more
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Antipyretic therapy: clinical pharmacology
2018Fever depends on a complex physiologic response to infectious agents and other conditions. To alleviate fever, many medicinal agents have been developed over a century of trying to improve upon aspirin, which was determined to work by inhibiting prostaglandin synthesis.
Jonathan J, Lee, Daniel L, Simmons
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Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 2016
The concept regarding the pathogenesis of pyrexia is almost exclusively concentrated on humoral mediatory mechanism. As per these views, exogenous pyrogens first persuade the formation of pyrogenic cytokines and these endogenous pyrogens order to increase the synthesis of prostaglandin E in different structures of the central nervous system (CNS).
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The concept regarding the pathogenesis of pyrexia is almost exclusively concentrated on humoral mediatory mechanism. As per these views, exogenous pyrogens first persuade the formation of pyrogenic cytokines and these endogenous pyrogens order to increase the synthesis of prostaglandin E in different structures of the central nervous system (CNS).
openaire +1 more source