Results 11 to 20 of about 236,558 (261)

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches. [PDF]

open access: yesClin Pharmacol Ther
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Yan D   +6 more
europepmc   +2 more sources

Variable impact on mortality of AIDS‐Defining events diagnosed during combination antiretroviral therapy: Not All AIDS‐defining conditions are created equal [PDF]

open access: yes, 2009
Background The extent to which mortality differs following individual acquired immunodeficiency syndrome (AIDS)–defining events (ADEs) has not been assessed among patients initiating combination antiretroviral therapy.
Justice, Amy   +121 more
core   +3 more sources

CD4+count-guided interruption of antiretroviral treatment [PDF]

open access: yes, 2006
BACKGROUND:Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV).METHODS:We ...
Babiker, A   +73 more
core   +1 more source

Self-Initiation of Antiretroviral Therapy in the Developing World: the Involvement of Private Pharmacies in an HIV Program. [PDF]

open access: yes, 2012
Self-initiation to antiretroviral treatment (ART) exposes the patient to the risk of drug toxicity, poor adherence to treatment, and escalates the development of drug resistance.
Buma, Deus   +8 more
core   +1 more source

Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study. [PDF]

open access: yes, 2012
Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood.
Giddy, Janet   +56 more
core   +2 more sources

Tuberculosis in antiretroviral treatment programs in lower income countries: availability and use of diagnostics and screening. [PDF]

open access: yes, 2013
In resource-constrained settings, tuberculosis (TB) is a common opportunistic infection and cause of death in HIV-infected persons. TB may be present at the start of antiretroviral therapy (ART), but it is often under-diagnosed. We describe approaches to
Samuel Ajayi   +110 more
core   +3 more sources

Determinação de lamivudina, estavudina e nevirapina, em comprimidos, por cromatografia líquida de alta eficiência

open access: yesQuímica Nova, 2006
A high performance liquid chromatography method was developed to quantify lamivudine, stavudine and nevirapine combined in tablets. The separation was carried out in less than 10 min using a phosphate buffer of pH 3.0 and acetonitrile (75:25, v/v) as ...
Gisele Rodrigues da Silva   +5 more
doaj   +1 more source

HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy [PDF]

open access: yes, 2008
We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258
Battegay, Manuel   +42 more
core   +2 more sources

Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration [PDF]

open access: yes, 2005
Background The genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral treatment is expanded to regions of the world where diverse non-subtype-B viruses predominate.Methods and ...
Wynhoven, B   +61 more
core   +2 more sources

Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial. [PDF]

open access: yes, 2015
Malnourished HIV-infected African adults are at high risk of early mortality after starting antiretroviral therapy (ART). We hypothesized that short-course, high-dose vitamin and mineral supplementation in lipid nutritional supplements would decrease ...
Chisenga, Molly   +37 more
core   +1 more source

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