Results 31 to 40 of about 236,558 (261)
Antiretroviral Therapy outcomes among adolescents and youth in rural Zimbabwe [PDF]
, 2012 Around 2 million adolescents and 3 million youth are estimated to be living with HIV worldwide. Antiretroviral outcomes for this group appear to be worse compared to adults. We report antiretroviral therapy outcomes from a rural setting in Zimbabwe among Bygrave, Helen, Bygrave Helen, Ncube Kwenzakwenkosi, Mtangirwa, Judith, Kwenzakwenkosi Ncube, Ford Nathan, Munyaradzi Dhodho, Ford, Nathan, Helen Bygrave, Katharina Kranzer, Mtangirwa Judith, Nathan Ford, Ncube, Kwenzakwenkosi, Judith Mtangirwa, Kranzer, Katharina, Munyaradzi, Dhodho, Dhodho Munyaradzi, Kranzer Katharina +17 morecore +2 more sourcesClass of antiretroviral drugs and the risk of myocardial infarction [PDF]
, 2007 BACKGROUND:We have previously demonstrated an association between combination antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this association differs according to the class of antiretroviral drugs.El-Sadr, W, De Wit, S, Phillips, Andrew, Friis-Moller, Nina, Weber, R, Reiss, Peter, Lundgren, JD, O. Kirk, W. M. El Sadr, Monforte, AD, R. Thiébaut, El-Sadr, Wafaa, R. Weber, Friis-Moller, N, N. Friis Møller, Law, MG, Lundgren, Jens D., Kirk, O, Thiebaut, Rodolphe, Fontas, E, Friis-Møller, Nina, De Wit, Stephane, Sabin, Caroline, P. Reiss, S. De Wit, A. N. Phillips, Sabin, CA, d'Arminio Monforte, Antonella, Law, Matthew G., Reiss, P, E. Fontas, Sabin, Caroline A., Lundgren, Jens D, DAD Study Grp, Monforte, Antonella d'Arminio, Phillips, Andrew N., J. D. Lundgren, Phillips, A, Fontas, Eric, M. G. Law, Weber, Rainer, C. A. Sabin, Kirk, Ole, A. d’Arminio Monforte, Law, Matthew +44 morecore +1 more sourceCervical cancer screen-and-treat services at HIV treatment sites in Nigeria: findings from the ICON-3 Practice Based Research Network
BMC Health Services ResearchBackground Cervical cancer remains a major public health concern in Nigeria, particularly among women living with HIV (WLHIV). While treatable if detected early, many WLHIV do not access cervical cancer screening and treatment services.Chibuike O. Chigbu, Cyril C. Dim, Stanley C. Eneh, Babayemi O. Olakunde, John O. Olawepo, Tonia C. Onyeka, Ijeoma U. Itanyi, Ngozi Idemili-Aronu, Nwamaka N. Lasebikan, Chinenye Bembir, Esther Audu, Omeje Ejiofor, Nicholas Hamman, Sagir Muhammad, Atakulu Lawrence, Odufunke Maijeh, Onyeji John, Idayat Yinusa, Bala Barka, Aisha Abdulrahmeen, Ezechukwu Paschalina, Obuchuku Nwafor, Gregory A. Aarons, Echezona E. Ezeanolue +23 moredoaj +1 more sourceEarly Antiretroviral Therapy in AIDS Patients Presenting With Toxoplasma gondii Encephalitis Is Associated With More Sequelae but Not Increased Mortality
Frontiers in Medicine, 2022 BackgroundEvidence on the optimal time to initiate antiretroviral therapy (ART) in the presence of toxoplasmic encephalitis (TE) is scarce. We compared the impact of early vs.Nadia Cubas-Vega, Nadia Cubas-Vega, Paola López Del-Tejo, Paola López Del-Tejo, Djane C. Baia-da-Silva, Djane C. Baia-da-Silva, Djane C. Baia-da-Silva, Vanderson Souza Sampaio, Vanderson Souza Sampaio, Vanderson Souza Sampaio, Vanderson Souza Sampaio, Bruno Araújo Jardim, Monique Freire Santana, Monique Freire Santana, Luiz Carlos Lima Ferreira, Luiz Carlos Lima Ferreira, Luiz Carlos Lima Ferreira, Luiz Carlos Lima Ferreira, Izabella Picinin Safe, Izabella Picinin Safe, Izabella Picinin Safe, Márcia A. Araújo Alexandre, Marcus Vinícius Guimarães Lacerda, Marcus Vinícius Guimarães Lacerda, Marcus Vinícius Guimarães Lacerda, Marcus Vinícius Guimarães Lacerda, Wuelton Marcelo Monteiro, Wuelton Marcelo Monteiro, Fernando Val, Fernando Val, Fernando Val, Fernando Val +31 moredoaj +1 more sourceLong‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods
Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).Kathryn B. Holroyd, Tyler Hamby, Carlo Sacdalan, Somchai Sriplienchan, Pathariya Promensa, Luxenaree Poonpitak, Netsiri Dumrongpisutikul, Eugène Kroon, Sandhya Vasan, Robert Paul, Ferron O'Campo, Lydie Trautmann, Phillip Chan, Serena Spudich, on behalf of the RV254/SEARCH 010 Study Team, Julie Ake, Sandhya Vasan, Lydie Trautmann, Merlin Robb, Trevor Crowell, Donn Colby, Diane Bolton, Shelly Krebs, Leigh Ann Eller, Morgane Rolland, Rasmi Thomas, Dominic Paquin Proulx, Suteeraporn Pinyakorn, Tyler Hamby, Mark de Souza, Ellen Turk, Amber Moodley, Gerald Quarles, Jintanat Ananworanich, Denise Hsu, Victoria Polonis, Nelson Michael, Sheila Peel, COL Eric Garges, Alexandra Schuetz, Siriwat Akapirat, Bessara Nantapinit, Pornsuk Visudhiphan, Saowanit Getchalarat, Nampueng Churikanont, Sangsulee Thamakaison, Somchai Sriplienchan, Carlo Sacdalan, Pathariya Promsena, Luxe‐naree Poonpitak, Eugene Kroon, Nitiya Chomchey, Jintana Intasan, Varaporn Pothipala, Ferron Ocampo, Nittaya Phanuphak, Nipat Teeratakulpisan, Yuwaree Pichitchok, Anchalee Avihingsanon, Opass Putcharoen, Kiat Ruxrungtham, Thanyawee Puthanakit, Sopark Manasnayakorn, Phandee Watanaboonyongcharoen, Rungsun Rerknimitr, Irini Sereti, Daniel Douek, Eli Bortiz, Frank Maldarelli, Mary Kearney, Serena Spudich, Phillip Chan, Lishomwa Ndhlovu, Guinevere Li, Michael Corley, Victor Valcour, Peter Hunt, Jacob Estes, Afam Okoye, Jeff Lifson, Claire Deleage, Nicolas Chomont, Andres Finzi, Lyle McKinnon, Henrik Zetterberg, Robert Siliciano, Robert Paul, Julie Mannarino, Jonathan Li, John Mellors, Josh Cytkor, Dan Barouch, Michael Seaman, Boris Juelg, Alex Shalek, Timothy Schacker, Ashley Haase, Mario Stevenson, Wenjun Li, Arthur Kim, Sharon Lewin, Adam Carrico, Susana Valente, Fred Hutchinson, Josh Schiffer, Guido Ferrari, Beau Ances, Alberto Bosque, Katharine Bar, Killian Pohl, David Ho, Yaoxing Huang, Michael Busch, Mohamed Abdel‐Mohsen, Johanna Gostner, Brian Agan, Fatah Kashanchi, Greg Laird, Kathryn Holroyd +118 morewiley +1 more sourceGuidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection [PDF]
, 2003 Although the pathogenesis of human immunodeficiency virus (HIV) infection and the general virologic and immunologic principles underlying the use of antiretroviral therapy are similar for all HIV-infected persons, there are unique considerations needed ...Health Resources and Services Administration, HRSA, National Institutes of Health, NIH, Antiretroviral Therapy and Medical Management of HIV-Infected Children, ATMMHC, National Pediatric and Family HIV Resource Center, NPHRC +3 morecore Timing of antiretroviral therapy in Cambodian hospital after diagnosis of tuberculosis: impact of revised WHO guidelines [PDF]
, 2013 OBJECTIVE: To determine if implementation of 2010 World Health Organization (WHO) guidelines on antiretroviral therapy (ART) initiation reduced delay from tuberculosis diagnosis to initiation of ART in a Cambodian urban hospital. METHODS: A retrospective Reaksmey Pe, Lorent, N., Pe, R., Sopheak Thai, Thai, S., Lynen, L., Natalie Lorent, Choun, K., van Griensven, J., Johan van Griensven, Kimcheng Choun, Lutgarde Lynen +11 morecore +1 more sourceThe latest evidence for possible HIV-1 curative strategies
Drugs in Context, 2018 Human immunodeficiency virus type 1 (HIV-1) infection remains a major health issue worldwide. In developed countries, antiretroviral therapy has extended its reach from treatment of people living with HIV-1 to post-exposure prophylaxis, treatment as ...Hanh Thi Pham, Thibault Mesplèdedoaj +1 more sourceImpact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy. [PDF]
, 2014 The objective of this study is to estimate life expectancies of HIV-positive patients conditional on response to antiretroviral therapy (ART)Richard Gilson, Margaret T. May, John Walsh, Chadwick, D, Gompels, Mark, Porter, Kholoud, Anderson, Jane, Delpech, V, UK, UKCHIVC, Leen, Clifford, Martin, F, Valerie Delpech, Sophie Jose, Hill, Teresa, Jose, Sophie, Pillay, Deenan, Sabin, Caroline, Chloe Orkin, Orkin, Chloe, Fabiola Martin, UK Collaborative HIV Cohort (UK CHIC) Study, ., Sabin, C, Hay, Phillip, Johnson, M, Martin Fisher, Gilson, Richard, Kholoud Porter, Fisher, M, Ainsworth, Jonathan, ?, ?, Johnson, Margaret, Gilson, R, Hay, P, Gompels, M, Phillip Hay, Nelson, Mark, Palfreeman, Adrian, Teresa Hill, Phillips, Andrew, Mackie, Nicky, Porter, K, May, Margaret T, Delpech, Valerie, Mark Nelson, UK Collaborative HIV Cohort (UK CHIC) Study, Fisher, Martin, Walsh, J, Babiker, Abdel, Hill, T, Schwenk, Achim, Adrian Palfreeman, Chadwick, David, Orkin, C, Winston, Alan, Ainsworth, J, Kegg, Stephen, Margaret Johnson, David Chadwick, Caroline Sabin, Walsh, John, Sachikonye, Memory, Nelson, M, Kegg, S, May, MT, Frank Post, Clifford Leen, Martin, Fabiola, Dunn, Daviad, Anderson, J, Gazzard, Brian, Post, Frank, Mark Gompels, Jose, S, May, Margaret T., Post, F, Palfreeman, A, Leen, C, Stephen Kegg, Jonathan Ainsworth, Jane Anderson +79 morecore +1 more sourceDeep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
Advanced Science, EarlyView.This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng +7 morewiley +1 more source