Results 31 to 40 of about 8,379,610 (258)

Update on highly active antiretroviral therapy: progress and strategies [PDF]

Biomedicine & Pharmacotherapy, 2000
HIV patients who have detectable viral loads (1,000-5,000 copies/mL) and/or evidence of immunologic dysfunction (CD4+ T-lymphocyte count < 500/mm3) should be treated with a potent combination antiretroviral regimen. Currently, this is to consist of two nucleoside reverse transcriptase inhibitors (NRTIs) with at least one protease inhibitor (PI), or a ...
Clumeck, Nathan, De Wit, Stéphane
openaire   +2 more sources

Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania. [PDF]

, 2008
\ud \ud Studies of antiretroviral therapy (ART) programs in Africa have shown high initial mortality. Factors contributing to this high mortality are poorly described.
Matee, Mecky I., Naman, Ezra, Bernard J Ngowi, Svein G Gundersen, Ngowi, Bernard J., Bruun, Johan Nikolai, Gundersen, Svein G., Aglen, H.E, Mecky I Matee, Sandvik, L., Aglen Henry E, Asgeir Johannessen, Johannessen, A., Henry E Aglen, Naman Ezra, Bruun Johan N, Matee, Mecky I, Ngowi, B.J, Ngowi Bernard J, Matee, M.I, Bruun, J.N, Ngowi, Bernard J, Aglen, Henry E., Leiv Sandvik, Sandvik Leiv, Sandvik, Leiv, Aglen, Henry E, Johannessen Asgeir, Matee Mecky I, Ezra Naman, Johan N Bruun, Johannessen, Asgeir, Gundersen, Svein G, Gundersen Svein G, Gundersen, S.G, Bruun, Johan N, Naman, E.   +36 more
core   +2 more sources

CD4+count-guided interruption of antiretroviral treatment [PDF]

, 2006
BACKGROUND:Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV).METHODS:We ...
Babiker, A, Lundgren, JD, Faetkenheuer, G., Rappoport, C, Hoy, Jennifer, El-Sadr, Wafaa, Arduino, RC, Grund, B, Abrams, DJ, Clumeck, Nathan, Strategies for Management of Antiretroviral Therapy (SMART) Stud, Clumeck, N., Gazzard, B, Neuhaus, J, Neaton, J. D., Lundgren, J. D., Darbyshire, J, Grund, Birgit, Hoy, J., Phillips, A., Fätkenheuer, Gerd, Neaton, James, Lundgren, Jens D, Cohn, D., Cohen, C. J., Mejia, JMR, Strategies Management Antiretrovir, Darbyshire, J., Emery, S, Klingman, Karin, Darbyshire, Janet, Markowitz, Norman, Emery, Sean, Cohn, David V., Cooper, David, Gordin, Fred, Emery, S., Losso, M, Losso, Marcello, Klingman, K, Neaton, JD, Clumeck, N, Markowitz, N., Babiker, Abdel, Cooper, D., Losso, M., Mejia, J. M. Ramos, Arduino, R. C., Gordin, F, Fatkenheuer, G, Cohen, Calvin, Hoy, J, Neuhaus, J., El-Sadr, W. M., Grund, B., Klingman, K., El-Sadr, WM, Cohn, D, Gazzard, Brian, Burman, William, Burman, W., Abrams, D, Cohen, CJ, Gazzard, B., Arduino, Roberto, Markowitz, N, Gordin, F., Babiker, A., Burman, W, Cooper, D, Abrams, D., Phillips, Andrew N., Phillips, A, Rappoport, C.   +73 more
core   +1 more source

Real-World Experience With Lenacapavir and/or Fostemsavir as Emerging Therapies for the Management of Multidrug-Resistant HIV-1 in Southeastern France. [PDF]

J Med Virol
ABSTRACT Lenacapavir and fostemsavir, two recently approved anti‐HIV‐1 agents, are promising options for people with difficult‐to‐treat HIV; however, real‐world data remain limited. This study aimed to describe the epidemiological, clinical, and virological profiles of people receiving combination antiretroviral regimens, including lenacapavir and/or ...
Boujamline S, Boschi C, Bes-Barlandier H, Tomei C, Menard A, Mokhtari S, Ravaux I, Belkhir Y, Neant N, Solas C, Colson P, Million M.   +11 more
europepmc   +2 more sources

Antiretroviral Therapy outcomes among adolescents and youth in rural Zimbabwe [PDF]

, 2012
Around 2 million adolescents and 3 million youth are estimated to be living with HIV worldwide. Antiretroviral outcomes for this group appear to be worse compared to adults. We report antiretroviral therapy outcomes from a rural setting in Zimbabwe among
Bygrave, Helen, Bygrave Helen, Ncube Kwenzakwenkosi, Mtangirwa, Judith, Kwenzakwenkosi Ncube, Ford Nathan, Munyaradzi Dhodho, Ford, Nathan, Helen Bygrave, Katharina Kranzer, Mtangirwa Judith, Nathan Ford, Ncube, Kwenzakwenkosi, Judith Mtangirwa, Kranzer, Katharina, Munyaradzi, Dhodho, Dhodho Munyaradzi, Kranzer Katharina   +17 more
core   +2 more sources

Does direct observation of antiretroviral therapy improve outcomes for HIV/AIDS patients compared to non-observed therapy?: A systematic review and meta-analysis of randomized-controlled trials [PDF]

, 2009
Includes bibliographical references.Highly active antiretroviral therapy (HAART) has dramatically affected the course of HIV disease, resulting in a significant reduction in AIDS-related morbidity and mortality in both developed and developing ...
Ford, Nathan
core   +1 more source

Classical and alternative macrophages have impaired function during acute and chronic HIV-1 infection

Brazilian Journal of Infectious Diseases, 2017
Objectives: Three decades after HIV recognition and its association with AIDS development, many advances have emerged – especially related to prevention and treatment.
Leonardo J. Galvão-Lima, Milena S. Espíndola, Luana S. Soares, Fabiana A. Zambuzi, Maira Cacemiro, Caroline Fontanari, Valdes R. Bollela, Fabiani G. Frantz   +7 more
doaj   +1 more source

Hematological parameters abnormalities and associated factors in HIV-positive adults before and after highly active antiretroviral treatment in Goba Referral Hospital, southeast Ethiopia: A cross-sectional study

SAGE Open Medicine, 2021
Objectives: Hematological abnormalities of the major blood cell lines are frequently reported in patients with HIV-1 infection, in patients without antiretroviral therapy, and during the advanced stages of the disease.
Negesso Duguma, Girum Tesfaye Kiya, Wondimagegn Adissu Maleko, Lealem Gedefaw Bimerew   +3 more
doaj   +1 more source

HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy [PDF]

, 2008
We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258
Battegay, Manuel, Günthard, Huldrych F, Gaudieri, S., Swiss, HIV Cohort Study, John, Mina, Nolan, David, James, Ian, Furrer, H, Schmid, P, Battegay, M., McKinnon, E, Rauch, A., Swiss HIV Cohort Study, ., McKinnon, E., Telenti, A, Günthard, Huldrych F., Schmid, Patrick, Rauch, A, John, M., James, I, Furrer, Hansjakob, Hirschel, Bernard, Telenti, Amalio, Schmid, P., Furrer, H., Rauch, Andri, John, M, Günthard, H.F., Mallal, Simon, Telenti, A., McKinnon, Elizabeth, Nolan, D., Günthard, H F, Hirschel, B, Günthard, H. F., Battegay, M, Hirschel, B., Nolan, D, Mallal, S, James, I., Gaudieri, Silvana, Mallal, S., Gaudieri, S   +42 more
core   +2 more sources

Lamivudine’s hypersensitivity in an HIV infected patient: case report

Medicina, 2017
Relevance: To report a case of hypersensitivity to lamivudine, a medicine that is considered safe and is indicated as part of the initial therapy for HIV infected patients.
Vitor R. G. A. Valviesse, Leonardo I. de Pinho, Rodrigo F. Freitas, Andrea G. Varon, Alberto S. Lemos   +4 more
doaj   +1 more source