Results 281 to 290 of about 175,256 (310)
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Overview of Antiretroviral Therapy
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1994All of the agents that are available for the treatment of human immunodeficiency viral infection belong to the class of drugs called nucleoside analogs that act on the virus's reverse transcriptase enzyme. As their use expanded for increasing cohorts of patients and stages of disease, it became clear that additional agents were required that would act ...
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Pediatric Antiretroviral Therapy
2019Human immunodeficiency virus (HIV) is one of the most serious pediatric infectious diseases, affecting around 3 million children and adolescents worldwide. Lifelong antiretroviral treatment (ART) provides multiple benefits including sustained virologic suppression, restoration and preservation of immune function, decreased morbidity and mortality, and ...
Sahera, Dirajlal-Fargo +2 more
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Combination antiretroviral therapy
Expert Opinion on Pharmacotherapy, 2011Combination antiretroviral therapy (cART) was one of the greatest achievements in medicine in the twentieth century. It has rapidly evolved during the last 10 years from suboptimal monotherapy to an effective triple therapy that can change the natural history of HIV-1 infection from a deadly disease to a chronic, manageable condition.
Pere, Domingo, Francesc, Vidal
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Protein Binding in Antiretroviral Therapies
AIDS Research and Human Retroviruses, 2003There is marked variability in the extent to which the three classes of antiretroviral (ARV) drugs bind to plasma proteins (99%). Protease inhibitors (PIs), with the exception of indinavir, are more than 90% protein bound, mainly to alpha1-acid glycoprotein (AAG).
Boffito, Marta +6 more
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Initiation of antiretroviral therapy
Current Opinion in Internal Medicine, 2006Until there is a therapy or a vaccine that can eradicate HIV infection, it is important to continue debating the issues of when and how to use the many antiviral agents licensed as initial treatment since there remain many areas of uncertainty.Early initiation of treatment may be beneficial in terms of HIV progression but it has to be weighed against ...
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UPDATE ON ANTIRETROVIRAL THERAPY
Radiologic Clinics of North America, 1997The availability of 11 antiretroviral agents has greatly expanded options in the treatment of HIV-infected patients. Newer treatment strategies using combination therapy have significantly improved outcomes for patients with all stages of infection.
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[Antiretroviral therapy and pregnancy].
Therapeutische Umschau. Revue therapeutique, 2005Whereas the perinatal transmission rate with untreated HIV positive women is around 30%, the results of Pediatric AIDS Clinical Trials Group in 1994 showed a reduction by nearly 70% with Zidovudin chemoprophylaxis. The transmission rate can even be reduced to under 2%, if a cesarean section before onset of labour and before premature rupture of ...
Wunder, D, Evison, John Marc
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2019
Abstract: This chapter is about antiretroviral therapy (ART). It includes the goals of antiretroviral therapy (according to the 2018 Department of Health and Human Services [DHHH] guidelines), and it covers recommendations for antiretroviral therapy, special co-factor considerations, and what antiretroviral regimen to start.
John G. Bartlett +2 more
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Abstract: This chapter is about antiretroviral therapy (ART). It includes the goals of antiretroviral therapy (according to the 2018 Department of Health and Human Services [DHHH] guidelines), and it covers recommendations for antiretroviral therapy, special co-factor considerations, and what antiretroviral regimen to start.
John G. Bartlett +2 more
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Presse medicale (Paris, France : 1983), 2001
SPARING ANTIPROTEASES: An antiprotease-sparing strategy can improve compliance and adhesion to antiretroviral treatments. Several studies have demonstrated that switching to neviparin or efavirenz can maintain viral suppression and allow satisfactory rise in CD4 counts with a significant reduction in the neviparin group.
S, Dominguez, F, Bricaire
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SPARING ANTIPROTEASES: An antiprotease-sparing strategy can improve compliance and adhesion to antiretroviral treatments. Several studies have demonstrated that switching to neviparin or efavirenz can maintain viral suppression and allow satisfactory rise in CD4 counts with a significant reduction in the neviparin group.
S, Dominguez, F, Bricaire
openaire +1 more source