Results 221 to 230 of about 3,216,105 (293)
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Reclassification of Antirheumatic Agents
Clinical Immunotherapeutics, 1994A proposed new classification of antirheumatic therapy nominates two major categories, as follows. 1 Symptom-modifying antirheumatic drugs (SM-ARDs) improve the symptoms and clinical features of inflammatory synovitis. They can be further categorised as: (I) nonsteroidal anti-inflammatory drugs; (II) corticosteroids; and (III) slower-acting ...
John Edmonds, John Edmonds
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Drugs, 2002
Several new drugs have become available for the treatment of patients with osteoarthritis and rheumatoid arthritis (RA). These agents include selective cyclooxygenase (COX)-2 inhibitors, leflunomide and anti-tumour necrosis factor (TNF)-alpha antagonists.
Nurmohamed, Michael T +2 more
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Several new drugs have become available for the treatment of patients with osteoarthritis and rheumatoid arthritis (RA). These agents include selective cyclooxygenase (COX)-2 inhibitors, leflunomide and anti-tumour necrosis factor (TNF)-alpha antagonists.
Nurmohamed, Michael T +2 more
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ChemInform Abstract: Antirheumatic Agents: Novel Methotrexate Derivatives Bearing a Benzoxazine or Benzothiazine Moiety. [PDF]
ChemInform, 1997 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
N. Kato +11 more
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Articular Pharmacokinetics of Protein-Bound Antirheumatic Agents
Clinical Pharmacokinetics, 1993By what mechanism do nonsteroidal anti-inflammatory drugs (NSAIDs) move from plasma into synovial fluid and back, and how does binding to plasma albumin in vitro relate to articular transport in vivo? To evaluate these issues, concurrent plasma and synovial fluid data of 8 different NSAIDs from 10 single-dose trials were analysed by a simple ...
Mary P. Wu +2 more
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Drug therapy reviews: Antirheumatic agents
American Journal of Health-System Pharmacy, 1979The pathophysiology, symptoms and drug treatment of rheumatic disease are reviewed. Antirheumatic drugs reviewed are salicylates (including aspirin, sodium salicylate, choline salicylate, choline magnesium salicylate, salsalate), phenylpropionic acid derivatives (fenoprofen, ibuprofen, naproxen), indole derivatives (sulindac, tolmetin and indomethacin),
R. Evens
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Topical antirheumatic agents as hydroxyl radical scavengers
International Journal of Pharmaceutics, 1995Camphor, capsaicin, ketoprofen, lavender oil, cineole, β-pinene and methyl nicotinate which are used in topical formulations for the relief of pain associated with rheumatic and musculo-skeletal disorders were assessed for hydroxyl radical scavenging properties.
Sara Denman +3 more
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The Antirheumatic Agents Sulphasalazine and Methotrexate Share an Anti-Inflammatory Mechanism
Rheumatology, 1995Increasingly, methotrexate (MTX) and sulphasalazine (SASP) are used initially for second-line therapy of rheumatoid arthritis (RA). Although SASP and MTX are commonly used, the mechanism(s) by which these drugs control the inflammation that characterizes RA have remained obscure.
B. Cronstein
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Antirheumatic agents and leukocyte recruitment
Biochemical Pharmacology, 1999Most anti-inflammatory agents used in the treatment of joint diseases exert inhibitory effects on leukocyte infiltration. Methotrexate, a disease-modifying drug, and corticosteroids also inhibit leukocyte accumulation during inflammation. However, the mechanisms of action of these different compounds on leukocytes vary and in the case of non-steroidal ...
M. Parnham
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JAMA, 1977
The new antirheumatic agents, fenoprofen calcium, naproxen, and tolmetin sodium, are effective in the management of rheumatoid arthritis. Their efficacy is comparable, but not superior, to that of aspirin in usual oral doses. These agents also may be useful in degenerative joint disease and ankylosing spondylitis and as analgesics and antipyretics ...
J. Lewis
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The new antirheumatic agents, fenoprofen calcium, naproxen, and tolmetin sodium, are effective in the management of rheumatoid arthritis. Their efficacy is comparable, but not superior, to that of aspirin in usual oral doses. These agents also may be useful in degenerative joint disease and ankylosing spondylitis and as analgesics and antipyretics ...
J. Lewis
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Current Opinion in Rheumatology, 2021
Purpose of review Several new therapeutic drugs are now available for the management of rheumatoid arthritis (RA). Given that RA has been associated with an increased risk of certain cancers like lymphoma and lung cancer, concern remains about the safety
Namrata Singh, Christopher I. Li
semanticscholar +1 more source
Purpose of review Several new therapeutic drugs are now available for the management of rheumatoid arthritis (RA). Given that RA has been associated with an increased risk of certain cancers like lymphoma and lung cancer, concern remains about the safety
Namrata Singh, Christopher I. Li
semanticscholar +1 more source