Results 231 to 240 of about 3,216,105 (293)

Physicochemical characteristics of human IgG Fc fragments that expose regulatory rheumatoid factor neoepitopes and may show promise as antirheumatic agents

Biotechnology and applied biochemistry, 2019
Previously, we showed that immunoglobulin G (IgG) Fc fragments can expose neoepitopes specific to antibodies that were named regulatory rheumatoid factor (regRF). RegRF confers resistance to experimental autoimmune diseases. Immunization of rats with rat
A. Sidorov, L. Beduleva, I. Menshikov, A. Terentiev, I. Cherepanov   +4 more
semanticscholar   +1 more source

A controlled study of chloroquine as an antirheumatic agent

Arthritis & Rheumatism, 1958
AbstractThe use of a double‐blind therapeutic study to determine the effects of chloroquine on rheumatoid arthritis demonstrated antirheumatic properties of this drug. The criteria of Lansbury were successfully combined with other objective measurements to provide data of statistical validity.
Evan Calkins, Alan S. Cohen
openaire   +3 more sources

Zyn-Linker delivery of antirheumatic agents

Immunologic Research, 1994
Despite our increasing ability to manage rheumatoid arthritis through systemic medication, refractory joints require local administration of more aggressive therapy in a substantial number of patients. These studies tested whether a new class of molecules designated Zyn-Linkers could deliver and retain therapeutics in a joint. Zyn-Linkers are synthetic
H. B. McIlvain, Ohlsson-Wilhelm Bm, S. A. Weeks, Lorinc R, M. R. McDevitt, K. A. Muirhead, Gray Bd, K. A. Sheth   +7 more
openaire   +3 more sources

Pulmonary Disease Due to Antirheumatic Agents

Clinics in Chest Medicine, 1990
Drug-induced lung disease presents several diagnostic and therapeutic problems to the clinician. This is especially true in the case of lung disease associated with antirheumatic agents in which pulmonary disease may be due to the underlying disorder.
John A. D. Cooper, R. J. Zitnik
openaire   +2 more sources

Clinical Significance of Drug Interactions with Antirheumatic Agents

Clinical Immunotherapeutics, 1996
Patients with rheumatoid arthritis often require treatment with more than 1 drug, and potential drug interactions are therefore important. Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed, and are known to interact with many other drugs in common usage by effects on protein binding, hepatic metabolism and renal clearance.
Sarah M. Miles, Howard A. Bird
openaire   +2 more sources

Separation methods for antibacterial and antirheumatism agents in plant medicines

Journal of Chromatography B, 2004
Traditional oriental medicines (TOM), with a very long history and many remarkable features, are very popular in Asian countries, especially in China, Japan and Korea. With the development of advanced analytical techniques, the modernization of traditional medicine has become a hot area in recent years and some herbal medicines have been increasingly ...
Wei Li, Dawei Wen, Yuping Liu, Huwei Liu
openaire   +3 more sources

Influence of Antirheumatic Agents on the Release of Histamine from Rat Peritoneal Mast Cells After an Antigen‐Antibody Reaction

, 1965
S. Norn
openalex   +2 more sources

Evaluation of Ibuprofen (Motrin)

JAMA, 1975
Ibuprofen is a new, mild analgesic agent that may be useful in the symptomatic treatment of rheumatoid arthritis and osteoarthritis. Results of clinical studies have shown that its beneficial effects in these conditions are comparable, but not superior, to those of aspirin. However, at recommended doses it has less anti-inflammatory effect than aspirin.
openaire   +2 more sources

Effect of a Benzylidene Derivative, a Novel Antirheumatic Agent, on IL-1 Production

Pharmacological Research, 1993
3,4-Diacetoxy benzylidene diacetate (ACP) is a prodrug of protocatechualdehyde (PAL). PAL significantly inhibited interleukin-1 (IL-1) production and release in human monocytes in a dose dependent fashion under lipopolysaccharide (LPS) stimulation.
Koju Watanabe, Yo Mori, Haruhisa Hayashi
openaire   +3 more sources

Section 2 Clinical experience with fenoprofen, a new antirheumatic agent

Current Medical Research and Opinion, 1974
SummaryThe authors review the studies which have been carried out on fenoprofen. Fenoprofen has been demonstrated to have anti-inflammatory, analgesic and antipyretic activity in both animals and man. It is an effective and well tolerated agent in the symptomatic treatment of patients with rheumatoid arthritis, degenerative joint disease, ankylosing ...
Walter M. Mikulaschek, Anthony S. Ridolfo   +1 more
openaire   +2 more sources