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Antirheumatic agents: novel methotrexate derivatives bearing a benzoxazine or benzothiazine moiety. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
H. Matsuoka +11 more
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A controlled study of chloroquine as an antirheumatic agent
Arthritis & Rheumatism, 1958AbstractThe use of a double‐blind therapeutic study to determine the effects of chloroquine on rheumatoid arthritis demonstrated antirheumatic properties of this drug. The criteria of Lansbury were successfully combined with other objective measurements to provide data of statistical validity.
Evan Calkins, Alan S. Cohen
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Topical antirheumatic agents as hydroxyl radical scavengers
International Journal of Pharmaceutics, 1995Camphor, capsaicin, ketoprofen, lavender oil, cineole, β-pinene and methyl nicotinate which are used in topical formulations for the relief of pain associated with rheumatic and musculo-skeletal disorders were assessed for hydroxyl radical scavenging properties.
M. Billany +3 more
semanticscholar +3 more sources
Zyn-Linker delivery of antirheumatic agents
Immunologic Research, 1994Despite our increasing ability to manage rheumatoid arthritis through systemic medication, refractory joints require local administration of more aggressive therapy in a substantial number of patients. These studies tested whether a new class of molecules designated Zyn-Linkers could deliver and retain therapeutics in a joint. Zyn-Linkers are synthetic
H. B. McIlvain +7 more
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JAMA, 1977
The new antirheumatic agents, fenoprofen calcium, naproxen, and tolmetin sodium, are effective in the management of rheumatoid arthritis. Their efficacy is comparable, but not superior, to that of aspirin in usual oral doses. These agents also may be useful in degenerative joint disease and ankylosing spondylitis and as analgesics and antipyretics ...
J. Lewis
semanticscholar +5 more sources
The new antirheumatic agents, fenoprofen calcium, naproxen, and tolmetin sodium, are effective in the management of rheumatoid arthritis. Their efficacy is comparable, but not superior, to that of aspirin in usual oral doses. These agents also may be useful in degenerative joint disease and ankylosing spondylitis and as analgesics and antipyretics ...
J. Lewis
semanticscholar +5 more sources
Pulmonary Disease Due to Antirheumatic Agents
Clinics in Chest Medicine, 1990Drug-induced lung disease presents several diagnostic and therapeutic problems to the clinician. This is especially true in the case of lung disease associated with antirheumatic agents in which pulmonary disease may be due to the underlying disorder.
John A. D. Cooper, R. J. Zitnik
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Clinical Significance of Drug Interactions with Antirheumatic Agents
Clinical Immunotherapeutics, 1996Patients with rheumatoid arthritis often require treatment with more than 1 drug, and potential drug interactions are therefore important. Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed, and are known to interact with many other drugs in common usage by effects on protein binding, hepatic metabolism and renal clearance.
Sarah M. Miles, Howard A. Bird
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Separation methods for antibacterial and antirheumatism agents in plant medicines
Journal of Chromatography B, 2004Traditional oriental medicines (TOM), with a very long history and many remarkable features, are very popular in Asian countries, especially in China, Japan and Korea. With the development of advanced analytical techniques, the modernization of traditional medicine has become a hot area in recent years and some herbal medicines have been increasingly ...
Wei Li, Dawei Wen, Yuping Liu, Huwei Liu
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Evaluation of Ibuprofen (Motrin)
JAMA, 1975Ibuprofen is a new, mild analgesic agent that may be useful in the symptomatic treatment of rheumatoid arthritis and osteoarthritis. Results of clinical studies have shown that its beneficial effects in these conditions are comparable, but not superior, to those of aspirin. However, at recommended doses it has less anti-inflammatory effect than aspirin.
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Effect of a Benzylidene Derivative, a Novel Antirheumatic Agent, on IL-1 Production
Pharmacological Research, 19933,4-Diacetoxy benzylidene diacetate (ACP) is a prodrug of protocatechualdehyde (PAL). PAL significantly inhibited interleukin-1 (IL-1) production and release in human monocytes in a dose dependent fashion under lipopolysaccharide (LPS) stimulation.
Koju Watanabe, Yo Mori, Haruhisa Hayashi
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