Results 61 to 70 of about 3,216,105 (293)

Upadacitinib for the treatment of psoriatic arthritis

Drugs in Context, 2023
Psoriatic arthritis is a chronic systemic inflammatory disease that presents with a variable clinical course and is typically associated with joint inflammation, together with cutaneous psoriasis.
Diogo Fonseca, Miguel Nogueira, Tiago Torres   +2 more
doaj   +1 more source

Understanding cisplatin resistance using cellular models [PDF]

, 2007
Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of the DNA adducts.
Davey, Mary W., Stordal, Britta
core   +2 more sources

Recommendations for the Use of Disease‐Modifying Antirheumatic Drugs in Pregnancy and Reproductive Health for Patients With Rheumatic Disease: A Scoping Review

Arthritis Care &Research, EarlyView.
Objective Autoimmune rheumatic diseases commonly affect individuals of childbearing age, with historically increased adverse pregnancy outcomes in this group. The advent of disease‐modifying antirheumatic drugs (DMARDs) has fostered more suitable conditions for pregnancy; however, this is accompanied by challenges in ensuring safe use in reproductive ...
Athena Chin, Alice Terrett, Mihye Kwon, Samuel Whittle, Catherine Hill   +4 more
wiley   +1 more source

Monitoring the transition of patients on biologics in rheumatoid arthritis: Consensus guidance for pharmacists

Pharmacy Practice, 2021
Background: Recent approvals for novel agents such as the small molecule Janus kinase inhibitors (JAKi), combined with the advent of biosimilars has widened the gamut of available therapeutic options in the treatment of rheumatoid arthritis (RA).
Denis Choquette , Jonathan Chan , Mohammad Bardi , Carolyn Whiskin, Gabriel Torani , Brennan K. Smith , Aaron Sihota   +6 more
doaj   +1 more source

The Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective The aim of this systematic review was to synthesise the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye, Chidozie E.Mbada, Clara T.Fatoye, Faatihah Niyi‐Odumosu, Ushotanefe Useh, Zalmai Hakimi, Francis Fatoye   +6 more
wiley   +1 more source

Conventional Synthetic Disease-Modifying Anti-rheumatic Drugs for Psoriatic Arthritis: Findings and Implications From a Patient Centered Longitudinal Study in Brazil

Frontiers in Pharmacology, 2022
Background: Conventional synthetic disease-modifying antirheumatic drugs are the first-line treatment to inhibit the progression of psoriatic arthritis.
Ronaldo José Faria, Ronaldo José Faria, Francisca Janiclecia Rezende Cordeiro, Jéssica Barreto Ribeiro dos Santos, Jéssica Barreto Ribeiro dos Santos, Juliana Alvares-Teodoro, Augusto Afonso Guerra Júnior, Francisco de Assis Acurcio, Michael Ruberson Ribeiro da Silva, Michael Ruberson Ribeiro da Silva   +9 more
doaj   +1 more source

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]

, 2014
BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus, Ganz, Peter, Graf, Jonathan, Grunfeld, Carl, Hsue, Priscilla Y, Imboden, John, Nitta, Elaine, Scherzer, Rebecca, Schnell Heringer, Amanda, Shigenaga, Judy, Wu, Yuaner   +10 more
core   +2 more sources

Advancements in Dissolving Microneedles for Effective Transdermal Delivery in Rheumatoid Arthritis Treatment

Advanced Materials Interfaces, EarlyView.
Rheumatoid arthritis, a chronic inflammatory joint disease, faces limitations with conventional therapies. Dissolving microneedles (DMNs) enable biocompatible, high‐capacity transdermal drug delivery. However, skin elasticity challenges their strength, limiting drug release depth.
Wangrui Peng, MeeiChyn Goh, Jie Lan, Meng Du, Zhiyi Chen   +4 more
wiley   +1 more source

Dose-Dependent Impairment of the Immune Response to the Moderna-1273 mRNA Vaccine by Mycophenolate Mofetil in Patients with Rheumatic and Autoimmune Liver Diseases

Vaccines, 2022
The purpose of this study was to evaluate the efficacy and safety of the Moderna-1273 mRNA vaccine for SARS-CoV-2 in patients with immune-mediated diseases under different treatments.
Maria De Santis, Francesca Motta, Natasa Isailovic, Massimo Clementi, Elena Criscuolo, Nicola Clementi, Antonio Tonutti, Stefano Rodolfi, Elisa Barone, Francesca Colapietro, Angela Ceribelli, Matteo Vecellio, Nicoletta Luciano, Giacomo Guidelli, Marta Caprioli, Clara Rezk, Lorenzo Canziani, Elena Azzolini, Luca Germagnoli, Nicasio Mancini, Ana Lleo, Carlo Selmi   +21 more
doaj   +1 more source

Risk of Herpes Zoster in Individuals on Biologics, DMARDS and/or Corticosteroids for Autoimmune Diseases:A Systematic Review and Meta-Analysis [PDF]

, 2016
Background: Studies examining the risk of herpes zoster (HZ) associated with immunosuppressants, such as biologics, non-biological disease modifying agents (nbDMARDs) or corticosteroids, have generated conflicting results.
Alarcón-Segovia, Bachelez, Bejarano, Bongartz, Braun, Brenner, Bresnihan, Cardiel, Che, Chen, Choy, Cohen, Cutolo, Dechartres, Dixon, Dixon, Dreiher, Egger, Emery, Emery, Fleischmann, Fleischmann, Furie, Furst, Galloway, Genovese, Genovese, Gupta, Gupta, Harpaz, Hayward, Higgins, Higgins, Hoes, Kameda, Kawai, Keystone, Kost, Kourbeti, Kremer, Kremer, Kremer, Kremer, Lal, Leonardi, Long, McDonald, Merrill, Moher, Moreland, Moutsopoulos, Nakajima, Nishimoto, Osterman, Oxman, Oxman, Papp, Pappas, Peto, Rutgeerts, Sampathkumar, Sandborn, Sandborn, Schiff, Schreiber, Segan, Shah, Singh, Smitten, Smolen, Smolen, Spittal, Strangfeld, Stroup, Sweeting, Takeuchi, Tanaka, Tanaka, van der Heijde, van Vollenhoven, Veetil, Weiner, Wells, Winthrop, Winthrop, Winthrop, Wolfe, Yamamoto, Yawn, Yawn, Youssef, Yun, Zhang, Zisman, Zorzela   +94 more
core   +1 more source