Results 51 to 60 of about 1,565,970 (254)

Similar effects of disease-modifying antirheumatic drugs, glucocorticoids, and biologic agents on radiographic progression in rheumatoid arthritis: Meta-analysis of 70 randomized placebo-controlled or drug-controlled studies, including 112 comparisons

, 2010
To define the differences in effects on joint destruction in rheumatoid arthritis (RA) patients between therapy with single and combination disease-modifying antirheumatic drugs (DMARDs), glucocorticoids, and biologic ...
Niels Graudal, Jürgens, Gesche, Graudal, Niels, Gesche Jürgens   +3 more
core   +1 more source

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

Arthritis Care &Research, EarlyView.
Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis.
Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman   +4 more
wiley   +1 more source

Antibody engineering to develop new antirheumatic therapies [PDF]

There has been a therapeutic revolution in rheumatology over the past 15 years, characterised by a move away from oral immunosuppressive drugs toward parenteral targeted biological therapies.
Isaacs JD
core   +4 more sources

Biological treatment predictors and gender-based clinical features in Takayasu arteritis: A single-center cohort from Western Türkiye

Ulusal Romatoloji Dergisi
Objective: Takayasu arteritis (TAK) is a rare large-vessel vasculitis with female predominance, affecting the aorta and its branches. Although many cohorts have been described, predictors of biologic therapy use and gender-related differences in clinical
Dilara Bulut Gökten, Ömer Atakan Soğur, Rıdvan Mercan   +2 more
doaj   +1 more source

Eosinophilic fasciitis after parasite infection

Rheumatology, 2016
Eosinophilic fasciitis is a systemic inflammatory disease characterized by symmetrical swelling and skin induration of the distal portions of the arms and/or legs, evolving into a scleroderma-like appearance, accompanied by peripheral blood eosinophilia.
Marta Oliveira, Fabia Patinha, Antonio Marinho   +2 more
doaj   +1 more source

Biological Therapies in Inflammatory Myopathies

Rambam Maimonides Medical Journal, 2023
Idiopathic inflammatory myopathies (IIM) are a rare group of disorders that feature progressive immune-mediated skeletal muscle destruction along with skin, lung, and joint involvement.
Abd El Haleem Natour, Shaye Kivity
doaj   +1 more source

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms

, 2020
Despite the development of targeted therapies, conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) remain the cornerstone of treatment of rheumatoid arthritis (RA).
Anić, Branimir, Padjen, Ivan, Reihl Crnogaj, Mirna, Branimir Anić, Mirna Reihl Crnogaj, Ivan Padjen   +5 more
core   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

Arthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Profile of Patients with Rheumatoid Arthritis: a Descriptive Analysis

Brazilian Archives of Biology and Technology, 2022
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects many people worldwide and is the most common inflammatory joint disease of autoimmune origin.
Junior Garcia de Oliveira, Aline Ansbach Garabeli, Josélia Borba Daher   +2 more
doaj   +1 more source