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Joint Statement of EFSA and EMA on the presence of residues of phenylbutazone in horse meat [PDF]

open access: yesEFSA Journal, 2013
Controls in Member States have revealed the presence of phenylbutazone in horse carcasses intended for the food chain.  Following the request from the European Commission, the European Medicines Agency and the European Food Safety Authority jointly ...
European Food Safety Authority
doaj   +3 more sources

Effect of Phenylbutazone Administration on Insulin Sensitivity in Horses With Insulin Dysregulation [PDF]

open access: yesJournal of Veterinary Internal Medicine
Background Phenylbutazone is prescribed to manage pain caused by hyperinsulinemia‐associated laminitis. Phenylbutazone reduces glucose and insulin concentrations in horses with insulin dysregulation (ID) but the underlying mechanism of action is unknown.
Kate L. Kemp   +3 more
doaj   +2 more sources

Effect of phenylbutazone administration on the enteroinsular axis in horses with insulin dysregulation [PDF]

open access: yesJournal of Veterinary Internal Medicine
Background Phenylbutazone is prescribed for laminitis‐associated pain and decreases glucose and insulin responses to an oral glucose test (OGT) in horses with insulin dysregulation (ID).
Kate L. Kemp   +2 more
doaj   +2 more sources

Administration of Human Chorionic Gonadotropin Combined with Phenylbutazone at the Time of Embryo Transfer Synergistically Improves Pregnancy Rates in Dromedary Camels [PDF]

open access: yesVeterinary Sciences
Effective luteal support is crucial for successful pregnancy following embryo transfer in dromedary camels, highlighting the importance of maintaining adequate luteal function.
Mahmoud Moussa   +3 more
doaj   +2 more sources

Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications [PDF]

open access: yesJournal of Pharmaceutical Analysis, 2018
Three mesoporous silica excipients (Syloid® silicas AL-1 FP, XDP 3050 and XDP 3150) were formulated with a model drug known for its poor aqueous solubility, namely phenylbutazone, in an attempt to enhance the extent and rate of drug dissolution. Although
Laura J. Waters   +7 more
doaj   +4 more sources

Effect of phenylbutazone on insulin secretion in horses with insulin dysregulation [PDF]

open access: yesJournal of Veterinary Internal Medicine
Background Phenylbutazone is often prescribed to manage pain caused by hyperinsulinemia‐associated laminitis, but in diabetic people nonsteroidal anti‐inflammatory drugs increase insulin secretion and pancreatic activity.
Kate L. Kemp   +2 more
doaj   +2 more sources

Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White   +2 more
doaj   +2 more sources

From Veterinary Medicine to Illicit Drug Supply: Utilising Social Media to Explore the Rising Emergence of Veterinary Medicines in Human Health [PDF]

open access: yesBrain Sciences
Background/Objectives: The misuse of veterinary drugs is a growing concern, with increasing evidence of their presence in illicit drug markets and their use as alternatives to traditional substances. Methods: This study explores Reddit discussions on the
Josie Dunn   +4 more
doaj   +2 more sources

In vitro and in vivo evaluation of anti-inflammatory activities of ethanol extract from Lom-Am-Ma-Pruek remedy for pain relief [PDF]

open access: yesResearch in Pharmaceutical Sciences
Background and purpose: Lom-Am-Ma-Pruek (LAMP) remedy has been used in Thai traditional medicine to relieve pain associated with the inflammatory process.
Arunporn Itharat   +6 more
doaj   +2 more sources

Integrated analysis of gut metabolome, microbiome, and exfoliome data in an equine model of intestinal injury [PDF]

open access: yesMicrobiome
Background The equine gastrointestinal (GI) microbiome has been described in the context of various diseases. The observed changes, however, have not been linked to host function and therefore it remains unclear how specific changes in the microbiome ...
C. M. Whitfield-Cargile   +10 more
doaj   +2 more sources

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