Effect of Phenylbutazone Administration on Insulin Sensitivity in Horses With Insulin Dysregulation [PDF]
Journal of Veterinary Internal MedicineBackground Phenylbutazone is prescribed to manage pain caused by hyperinsulinemia‐associated laminitis. Phenylbutazone reduces glucose and insulin concentrations in horses with insulin dysregulation (ID) but the underlying mechanism of action is unknown.
Kate L. Kemp +3 more
doaj +3 more sources
Effect of phenylbutazone administration on the enteroinsular axis in horses with insulin dysregulation [PDF]
Journal of Veterinary Internal MedicineBackground Phenylbutazone is prescribed for laminitis‐associated pain and decreases glucose and insulin responses to an oral glucose test (OGT) in horses with insulin dysregulation (ID).
Kate L. Kemp +2 more
doaj +3 more sources
Effect of phenylbutazone on insulin secretion in horses with insulin dysregulation [PDF]
Journal of Veterinary Internal MedicineBackground Phenylbutazone is often prescribed to manage pain caused by hyperinsulinemia‐associated laminitis, but in diabetic people nonsteroidal anti‐inflammatory drugs increase insulin secretion and pancreatic activity.
Kate L. Kemp +2 more
doaj +3 more sources
The pharmacokinetics of phenylbutazone and its interaction with dexamethasone in chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2023 The present study aims to investigate the influence of dexamethasone administration on the pharmacokinetics of phenylbutazone and its plasma concentration as well as its pharmacological interaction in a chick model.
Sahar K. Abdulhamid, Yaareb J. Mousa
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Administration of Human Chorionic Gonadotropin Combined with Phenylbutazone at the Time of Embryo Transfer Synergistically Improves Pregnancy Rates in Dromedary Camels [PDF]
Veterinary SciencesEffective luteal support is crucial for successful pregnancy following embryo transfer in dromedary camels, highlighting the importance of maintaining adequate luteal function.
Mahmoud Moussa +3 more
doaj +2 more sources
Joint Statement of EFSA and EMA on the presence of residues of phenylbutazone in horse meat [PDF]
EFSA Journal, 2013 Controls in Member States have revealed the presence of phenylbutazone in horse carcasses intended for the food chain. Following the request from the European Commission, the European Medicines Agency and the European Food Safety Authority jointly ...
European Food Safety Authority
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From Veterinary Medicine to Illicit Drug Supply: Utilising Social Media to Explore the Rising Emergence of Veterinary Medicines in Human Health [PDF]
Brain SciencesBackground/Objectives: The misuse of veterinary drugs is a growing concern, with increasing evidence of their presence in illicit drug markets and their use as alternatives to traditional substances. Methods: This study explores Reddit discussions on the
Josie Dunn +4 more
doaj +2 more sources
Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism
Molecules, 2019 A drug design for safer phenylbutazone was been explored by reactivity and docking studies involving single electron transfer mechanism, as well as toxicological predictions.
Josivan da Silva Costa +1 more
exaly +3 more sources
BMJ, 1953 THIS REPORT evaluates the use of phenylbutazone (Butazolidin) for 800 patients with a variety of diseases. It covers a period of 30 months, from November 1950 to May 1953. During the first eight months phenylbutazone was used with equal parts of aminopyrine as a mixture known in the United States as Butapyrin and in Europe as Irgapyrin.
W C, KUZELL +4 more
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Correction: Phenylbutazone concentrations in synovial fluid following administration via intravenous regional limb perfusion in the forelimbs of six adult horses [PDF]
Frontiers in Veterinary ScienceMolly O'Brien +7 more
doaj +2 more sources