Results 11 to 20 of about 5,109 (163)

The pharmacokinetics of phenylbutazone and its interaction with dexamethasone in chicks [PDF]

Iraqi Journal of Veterinary Sciences, 2023
The present study aims to investigate the influence of dexamethasone administration on the pharmacokinetics of phenylbutazone and its plasma concentration as well as its pharmacological interaction in a chick model.
Sahar K. Abdulhamid, Yaareb J. Mousa
doaj   +1 more source

Survey describing the perspectives and practices of Australian veterinarians to pain management in horses. [PDF]

Aust Vet J
Objective To describe Australian practices and attitudes regarding equine analgesia. Study Design Cross‐sectional anonymous, voluntary survey of Australian veterinarians treating equine patients. Methods Australian veterinarians in equine or mixed practices completed a six‐section, 60‐question survey between November 2019 to August 2020.
Whitelock A, Goodwin W, Dryburgh L, Mshelbwala PP, Rae L, Marwedel L, Lok T, Kemp K, Stewart AJ.   +8 more
europepmc   +2 more sources

Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses

Journal of Veterinary Internal Medicine, 2021
Background Gastrointestinal (GI) injury and dysbiosis are adverse events associated with nonsteroidal anti‐inflammatory drug (NSAID) use in horses. Phenylbutazone has been shown to alter GI barrier function both in vitro and ex vivo, but its effects on ...
Canaan M. Whitfield‐Cargile, Michelle C. Coleman, Noah D. Cohen, Ana M. Chamoun‐Emanuelli, Cristobal Navas DeSolis, Taylor Tetrault, Ryan Sowinski, Amanda Bradbery, Mattea Much   +8 more
doaj   +1 more source

Joint Statement of EFSA and EMA on the presence of residues of phenylbutazone in horse meat [PDF]

EFSA Journal, 2013
Controls in Member States have revealed the presence of phenylbutazone in horse carcasses intended for the food chain.  Following the request from the European Commission, the European Medicines Agency and the European Food Safety Authority jointly ...
European Food Safety Authority
doaj   +1 more source

“Ain’t She a Bute?”: The Importance of Proper History Taking in a Case of Inappropriate Use of Horse NSAID in a Human

Clinics and Practice, 2021
A 41-year-old woman with no significant past medical history presented to the hospital with complaints of nausea, vomiting, and generalized weakness over two weeks.
Khalid Sawalha, Ryan James, Farah Mazahreh, Harmeen Goraya, Fuad Habash   +4 more
doaj   +1 more source

Study of photolysis on the active material Phenylbutazone in veterinarian drug Isophen [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2013
The veterinary medicine isophen was used in this study. Isophen contains phenylbutazone as active material .Numbers of samples of isophen were prepared and were determined absorbance were determined and comparison subjected to radiation for different ...
Hanan H. Flaeh, Wajeeh Y. Mohammed, Authman S. Ibrahim, Sattar S. Ibrahim   +3 more
doaj   +1 more source

Right dorsal colitis in horses: A multicenter retrospective study of 35 cases

Journal of Veterinary Internal Medicine, 2023
Background Right dorsal colitis (RDC) is a nonsteroidal anti‐inflammatory drug (NSAID) induced, protein losing enteropathy in horses associated with a high case fatality rate.
Jordan Flood, David Byrne, Jennifer Bauquier, Gustavo Ferlini Agne, Jessica C. Wise, Carlos E. Medina‐Torres, Kelly Wood, Olivia Sullivan, Allison J. Stewart   +8 more
doaj   +1 more source

Phenylbutazone concentrations in synovial fluid following administration via intravenous regional limb perfusion in the forelimbs of six adult horses

Frontiers in Veterinary Science, 2023
BackgroundPain management is critical to equine welfare with non-steroidal anti-inflammatory drugs (NSAID) commonly used in horses. However, systemic NSAID use is limited by harmful gastrointestinal and renal side effects.
Molly O’Brien, Jonathan P. Mochel, Jonathan P. Mochel, Jonathan P. Mochel, Kevin Kersh, Chong Wang, Chong Wang, Jarrod Troy   +7 more
doaj   +1 more source

CRECTROPHOTOMETRIC DETERMINATION OF PHENYLBUTAZONE AND OXYPHENBUTAZONE THROUGH CONDENSATION WITH P-DIMETHYLAMINOBENZALDEHYDE

Zagazig Journal of Pharmaceutical Sciences, 1997
P-Dimethylaminobenzaldehyde is used for colorimetric determination of phenylbutazone and oxyphenbutazone both in pure form and in their tablets. The reaction proceeds via first formation of aldol intermediate which suffers aminolysis by piperidine with ...
Gehard Rücker , Magda Ayad , Mohamed El-Sadek , Samia Moustafa   +3 more
doaj   +1 more source

Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications

Journal of Pharmaceutical Analysis, 2018
Three mesoporous silica excipients (Syloid® silicas AL-1 FP, XDP 3050 and XDP 3150) were formulated with a model drug known for its poor aqueous solubility, namely phenylbutazone, in an attempt to enhance the extent and rate of drug dissolution. Although
Laura J. Waters, John P. Hanrahan, Joseph M. Tobin, Catherine V. Finch, Gareth M.B. Parkes, Shamsuddeen A. Ahmad, Faraj Mohammad, Maria Saleem   +7 more
doaj   +1 more source