Results 31 to 40 of about 7,100 (194)

Phenylbutazone in the horse: a review [PDF]

open access: yes, 1986
Phenylbutazone is an acidic, lipophilic, nonsteroidal anti-inflammatory drug (NSAID). It is extensively metabolized in the horse. The metabolites so far identified, oxyphenbutazone, y-hydroxyphenylbutazone and y-hydroxyoxyphenbutazone.
Kamerling, S.   +6 more
core   +1 more source

CRECTROPHOTOMETRIC DETERMINATION OF PHENYLBUTAZONE AND OXYPHENBUTAZONE THROUGH CONDENSATION WITH P-DIMETHYLAMINOBENZALDEHYDE

open access: yesZagazig Journal of Pharmaceutical Sciences, 1997
P-Dimethylaminobenzaldehyde is used for colorimetric determination of phenylbutazone and oxyphenbutazone both in pure form and in their tablets. The reaction proceeds via first formation of aldol intermediate which suffers aminolysis by piperidine with ...
Gehard Rücker   +3 more
doaj   +1 more source

Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications

open access: yesJournal of Pharmaceutical Analysis, 2018
Three mesoporous silica excipients (Syloid® silicas AL-1 FP, XDP 3050 and XDP 3150) were formulated with a model drug known for its poor aqueous solubility, namely phenylbutazone, in an attempt to enhance the extent and rate of drug dissolution. Although
Laura J. Waters   +7 more
doaj   +1 more source

Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White   +2 more
doaj   +1 more source

A comparative survey of veterinarians, equine owners, and equine keepers regarding the knowledge and implementation of legal requirements in Germany for the use and documentation of veterinary medicines in equines intended for slaughter.

open access: yesPLoS ONE, 2023
In Europe, equines destined for human consumption (hereafter called slaughter equines) are subject to the same restrictions of usage of veterinary drugs as other food-producing animals, with amendments regulated in the so-called 'positive list ...
Shary Tamara Schneider   +4 more
doaj   +2 more sources

Isostructurality among five solvates of phenylbutazone

open access: yes
This work describes the crystal structures of phenylbutazone 2:1 solvates with benzene, cyclohexane, 1,4-dioxane, tetrahydrofuran, tetrachloromethane, and chloroform. These solvates are isostructural, with the exception of the chloroform solvate.
Datta S   +5 more
core   +5 more sources

The medication violations in racehorses at Louisiana racetracks from 2016 to 2020

open access: yesVeterinary Medicine and Science, 2022
Introduction/Background The number of publications for most common drug violations in racehorses is limited. This study reports the most common medication violations in racehorses at four major racetracks in Louisiana between 2016 and 2020.
Pamela Waller   +4 more
doaj   +1 more source

Phenylbutazone: A Clinico-Pharmacological Study in Rheumatoid Arthritis [PDF]

open access: yes, 1975
A clinical trial of phenylbutazone in high dose - 300 mg daily - and low dose - 50 mg daily - is presented. By analysis of the data by different methods, significant differences in clinical efficacy were shown between the two therapeutic regimes.
Dick, W. C.   +4 more
core   +1 more source

Application of PC-SAFT and cubic equations of state for the correlation of solubility of some pharmaceutical and statin drugs in SC-CO2 [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2013
In this work, the solubilities of some anti-inflammatory (nabumetone, phenylbutazone and salicylamide) and statin drugs (fluvastatin, atorvastatin, lovastatin, simvastatin and rosuvastatin) were correlated using the Perturbed-Chain Statistical ...
Abdallah El Hadj. A.   +3 more
doaj   +1 more source

Ativação de plaquetas de eqüinos com laminite induzida e tratados com ketoprofeno, fenilbutazona e flunixin meglumina Platelets activation in equine with induced laminitis and treated with ketoprophen, phenylbutazone and flunixin meglumin

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Avaliou-se a ativação de plaquetas em 20 eqüinos com laminite induzida, tratados com ketoprofeno, fenilbutazona e flunixin meglumina. As alterações de plaquetas incluíram mudança de forma, alteração da relação entre os eixos maior e menor, aumento de ...
F.O. Paes Leme   +3 more
doaj   +1 more source

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