Results 21 to 30 of about 7,100 (194)

In vitro and in vivo evaluation of anti-inflammatory activities of ethanol extract from Lom-Am-Ma-Pruek remedy for pain relief [PDF]

Research in Pharmaceutical Sciences
Background and purpose: Lom-Am-Ma-Pruek (LAMP) remedy has been used in Thai traditional medicine to relieve pain associated with the inflammatory process.
Arunporn Itharat, Pun Thongmee, Krit Piwngam, Janjira Inprasit, Sunita Makchuchit, Pranporn Kuropakornpong, Neal M. Davies   +6 more
doaj   +2 more sources

Quantifying the Equine Pain Response to Paracetamol Administration in Horses With Chronic Lameness Already Receiving Non-Steroidal Anti-Inflammatories. [PDF]

Vet Med Sci
In geriatric horses with chronic lameness receiving NSAIDs, adjunct oral paracetamol (20 mg/kg BID) showed no significant improvement in lameness severity. Weekly subjective scoring and objective gait analysis revealed no differences versus baseline or post‐treatment, indicating limited additional analgesic benefit in this population.
Conduit S, Bowen M, Bailey J, Redpath A.
europepmc   +2 more sources

Interaction of meloxicam and phenylbutazone on the level of cyclooxygenase-2 in mice [PDF]

Iraqi Journal of Veterinary Sciences, 2022
The reason for the recent study was to inspect the therapeutic efficacy of meloxicam and phenylbutazone alone with their analgesic interaction and their subsequent inhibitory interaction at the level of cyclooxygenase-2 in mice.
Yaareb J. Mousa, Khalil A. Khalil, Mahmood B. Mahmood   +2 more
doaj   +1 more source

Field-applicable low-intensity exercise induces bronchodilation in horses with severe asthma. [PDF]

Equine Vet J
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Mainguy-Seers S, Grondin SM, Lavoie JP.
europepmc   +2 more sources

Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses

Journal of Veterinary Internal Medicine, 2021
Background Gastrointestinal (GI) injury and dysbiosis are adverse events associated with nonsteroidal anti‐inflammatory drug (NSAID) use in horses. Phenylbutazone has been shown to alter GI barrier function both in vitro and ex vivo, but its effects on ...
Canaan M. Whitfield‐Cargile, Michelle C. Coleman, Noah D. Cohen, Ana M. Chamoun‐Emanuelli, Cristobal Navas DeSolis, Taylor Tetrault, Ryan Sowinski, Amanda Bradbery, Mattea Much   +8 more
doaj   +1 more source

“Ain’t She a Bute?”: The Importance of Proper History Taking in a Case of Inappropriate Use of Horse NSAID in a Human

Clinics and Practice, 2021
A 41-year-old woman with no significant past medical history presented to the hospital with complaints of nausea, vomiting, and generalized weakness over two weeks.
Khalid Sawalha, Ryan James, Farah Mazahreh, Harmeen Goraya, Fuad Habash   +4 more
doaj   +1 more source

Study of photolysis on the active material Phenylbutazone in veterinarian drug Isophen [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2013
The veterinary medicine isophen was used in this study. Isophen contains phenylbutazone as active material .Numbers of samples of isophen were prepared and were determined absorbance were determined and comparison subjected to radiation for different ...
Hanan H. Flaeh, Wajeeh Y. Mohammed, Authman S. Ibrahim, Sattar S. Ibrahim   +3 more
doaj   +1 more source

Right dorsal colitis in horses: A multicenter retrospective study of 35 cases

Journal of Veterinary Internal Medicine, 2023
Background Right dorsal colitis (RDC) is a nonsteroidal anti‐inflammatory drug (NSAID) induced, protein losing enteropathy in horses associated with a high case fatality rate.
Jordan Flood, David Byrne, Jennifer Bauquier, Gustavo Ferlini Agne, Jessica C. Wise, Carlos E. Medina‐Torres, Kelly Wood, Olivia Sullivan, Allison J. Stewart   +8 more
doaj   +1 more source

Phenylbutazone concentrations in synovial fluid following administration via intravenous regional limb perfusion in the forelimbs of six adult horses

Frontiers in Veterinary Science, 2023
BackgroundPain management is critical to equine welfare with non-steroidal anti-inflammatory drugs (NSAID) commonly used in horses. However, systemic NSAID use is limited by harmful gastrointestinal and renal side effects.
Molly O’Brien, Jonathan P. Mochel, Jonathan P. Mochel, Jonathan P. Mochel, Kevin Kersh, Chong Wang, Chong Wang, Jarrod Troy   +7 more
doaj   +1 more source

Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats

, 1997
Phenylbutazone was administered intravenously and orally to six goats as a single dose of 4.4 mg/kg and its disposition and bioavailability and the disposition of its active metabolite, oxyphenbutazone, in plasma were investigated, The effect of the ...
Welsh, E., McKellar, Quintin, Cheng, Z., Nolan, A.   +3 more
core   +6 more sources