Results 21 to 30 of about 7,222 (196)

Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats

open access: yes, 1997
Phenylbutazone was administered intravenously and orally to six goats as a single dose of 4.4 mg/kg and its disposition and bioavailability and the disposition of its active metabolite, oxyphenbutazone, in plasma were investigated, The effect of the ...
Welsh, E.   +3 more
core   +6 more sources

Effects of phenylbutazone, firocoxib, and dipyrone on the diuretic response to furosemide in horses

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Treatment with phenylbutazone (nonselective COX inhibitor) decreases the diuretic and natriuretic effects of furosemide by nearly 30% but the effects of COX‐2 specific inhibitors (firocoxib) and atypical NSAIDs (dipyrone) are unknown ...
Julianne M. White   +2 more
doaj   +1 more source

A comparative survey of veterinarians, equine owners, and equine keepers regarding the knowledge and implementation of legal requirements in Germany for the use and documentation of veterinary medicines in equines intended for slaughter.

open access: yesPLoS ONE, 2023
In Europe, equines destined for human consumption (hereafter called slaughter equines) are subject to the same restrictions of usage of veterinary drugs as other food-producing animals, with amendments regulated in the so-called 'positive list ...
Shary Tamara Schneider   +4 more
doaj   +2 more sources

The medication violations in racehorses at Louisiana racetracks from 2016 to 2020

open access: yesVeterinary Medicine and Science, 2022
Introduction/Background The number of publications for most common drug violations in racehorses is limited. This study reports the most common medication violations in racehorses at four major racetracks in Louisiana between 2016 and 2020.
Pamela Waller   +4 more
doaj   +1 more source

APTES-Modified SBA-15 as a Non-Toxic Carrier for Phenylbutazone

open access: yes, 2022
Improvement of the bioavailability of poorly soluble medicinal substances is currently one of the major challenges for pharmaceutical industry. Enhancing the dissolution rate of those drugs using novel methods allows to increase their bioavailability. In
Adrianna Dadej   +8 more
core   +1 more source

Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

open access: yesMolecules, 2019
A drug design for safer phenylbutazone was been explored by reactivity and docking studies involving single electron transfer mechanism, as well as toxicological predictions.
Rosivaldo S. Borges   +10 more
doaj   +1 more source

Application of PC-SAFT and cubic equations of state for the correlation of solubility of some pharmaceutical and statin drugs in SC-CO2 [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2013
In this work, the solubilities of some anti-inflammatory (nabumetone, phenylbutazone and salicylamide) and statin drugs (fluvastatin, atorvastatin, lovastatin, simvastatin and rosuvastatin) were correlated using the Perturbed-Chain Statistical ...
Abdallah El Hadj. A.   +3 more
doaj   +1 more source

[Sweet's syndrome and phenylbutazone-induced sialadenitis]

open access: yes, 2008
International audienceBACKGROUND: Phenylbutazone frequently induces a range of potentially dangerous adverse reactions. We report a case of Sweet's syndrome with sialadenitis induced by phenylbutazone.
Girardin, P.   +3 more
core   +1 more source

Phenylbutazone: A Clinico-Pharmacological Study in Rheumatoid Arthritis [PDF]

open access: yes, 1975
A clinical trial of phenylbutazone in high dose - 300 mg daily - and low dose - 50 mg daily - is presented. By analysis of the data by different methods, significant differences in clinical efficacy were shown between the two therapeutic regimes.
Dick, W. C.   +4 more
core   +1 more source

Ativação de plaquetas de eqüinos com laminite induzida e tratados com ketoprofeno, fenilbutazona e flunixin meglumina Platelets activation in equine with induced laminitis and treated with ketoprophen, phenylbutazone and flunixin meglumin

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Avaliou-se a ativação de plaquetas em 20 eqüinos com laminite induzida, tratados com ketoprofeno, fenilbutazona e flunixin meglumina. As alterações de plaquetas incluíram mudança de forma, alteração da relação entre os eixos maior e menor, aumento de ...
F.O. Paes Leme   +3 more
doaj   +1 more source

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