Case Report: A case of focal segmental glomerulosclerosis in Wilson’s disease induced by penicillamine [PDF]
Frontiers in MedicineWilson’s disease (WD) is a hereditary disorder that impairs copper metabolism. Both WD and its treatment with penicillamine are associated with renal impairment.
Qi Li +3 more
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Safety of penicillamine and trientine in the treatment of Wilson's disease: An analysis of the FDA Adverse Event Reporting System (FAERS) database. [PDF]
PLoS ONEBackgroundPenicillamine(D-Penicillamine) and trientine are first-line therapies for Wilson's Disease (WD), yet real-world data on their adverse events (AEs) remain scarce.
Wenlong Qian +12 more
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Pediatric Wilson Disease in Sudan: A Rare Case, Sudan Conflict and Diagnostic Challenges. [PDF]
Clin Case RepABSTRACT Wilson disease is rarely reported among African children. Wilson disease is due to a mutation in ATP7B on an autosomal recessive pattern, which causes defective copper excretion and copper accumulation in tissues such as liver and brain.
Mohammed AAA +8 more
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Annals of Indian Academy of Neurology, 2022 Background: Most centers in developing countries prefer chelation therapy with D-penicillamine for the management of Wilson's disease (WD) because of its easy availability and affordability. Neurological worsening following treatment with D-penicillamine
Madhan Kumar +5 more
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Wilson’s Disease with Late Hepatic Involvement [PDF]
Journal of Clinical and Diagnostic Research, 2023 Wilson’s Disease (WD) is an autosomal recessive condition that affects copper metabolism and manifests itself clinically in different ways. The diagnosis is indicated by low serum copper and ceruloplasmin concentrations, increased urine copper excretion ...
Mahavir Raghunath Mundra +3 more
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Penicillamine Nephropathy [PDF]
Nephron, 2008 8 patients who developed proteinuria whilst receiving penicillamine for rheumatoid arthritis have been studied. Light microscopy of renal biopsy specimens showed evidence of an extramembranous nephropathy in 6 cases, with epimembranous spikes infrequently described previously in association with penicillamine.
J H, Ross, F, McGinty, D G, Brewer
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Psychosis in Wilson's disease: A rare case presentation
Archives of Mental Health, 2021 Wilson's disease is an uncommon genetic disorder, in which abnormal copper accumulation occurs in various parts of the body. Approximately 30% of patients debut with neuropsychiatric symptoms posing a diagnostic challenge in the initial phase.
Kota Raga Sumedha +2 more
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Controlled administration of penicillamine reduces radiation exposure in critical organs during 64Cu-ATSM internal radiotherapy: a novel strategy for liver protection. [PDF]
PLoS ONE, 2014 PURPOSE: (64)Cu-diacetyl-bis (N (4)-methylthiosemicarbazone) ((64)Cu-ATSM) is a promising theranostic agent that targets hypoxic regions in tumors related to malignant characteristics.
Yukie Yoshii +10 more
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BMC Surgery, 2011 Background Adhesions formation is a significant postsurgical complication. At present, there is no effective method for preventing adhesions formation 1, although barrier products such as Dextran (Dex) 2 and sodium hyaluronate (SH) 3 have proved the most
Xi Dong +4 more
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Penicillamine-induced skin striae atrophicae in Wilson's disease: A report of 3 cases [PDF]
Jichu yixue yu linchuangObjective To analyze the clinical characteristics of 3 patients with Wilson's disease who suffered from skin striae atrophicae after treatment with penicillamine, and to conduct literature review to extensively profile adverse events of penicillamine ...
YUAN Sunbixin, ZHANG Zhenjie, QIU Zhengqing
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