D-penicillamine treatment of copper-associated hepatitis in Labrador retrievers
d-penicillamine is effectively used in the lifelong treatment of copper toxicosis in Bedlington terriers and Wilson’s disease in humans. A complex form of copper-associated hepatitis has recently been characterized in the Labrador retriever.
Tissue Repair +9 more
core +2 more sources
Penicillamine-associated cutis laxa and milia en plaque - case report and review of cutaneous changes associated with penicillamine [PDF]
Penicillamine-induced skin changes are rare and include: hypersensitivity reactions, autoimmune reactions, and cutaneous elastoses. We report a case of a 73-year-old man with cystinuria taking penicillamine for over 50 years who presented with ...
Vajdi, Tina +2 more
core +1 more source
Penicillamine-Induced Membranous Nephropathy in an Adolescent with Wilson’s Disease [PDF]
Membranous nephropathy may present in any age group. While it is one of the most common causes of adult nephrotic syndrome, it is a rare histologic entity in the paediatric population.
Ana Paula Serrão +5 more
core +1 more source
Rhabdomyolysis and muscle necrosis induced by lead poisoning
A case is presented on a 40-year-old male with chronic lead poisoning with loss of consciousness, rhabdomyolysis, and acute renal failure after occupational exposure.
Behnaz Ansari +4 more
doaj +1 more source
EFFECT OF COPPER SULPHATE POLLUTION AND ITS ANTIDOTE PENICILLAMINE ON SERUM AND BRAIN TISSUES MARKERS OF ALBINO RATS [PDF]
Background: Copper is an essential trace element and is required for many metabolic functions. Aim of work: The present study was designed to study the negative impact of excess copper sulphate on the central neural function of albino rats and studying ...
Doaa Abdel-Fattah +4 more
doaj +1 more source
D-Penicillamine Induced Degenerative Dermopathy in a Patient with Wilson Disease
D-penicillamine induced degenerative dermatosis include, among others, elastosis perforans serpiginosa, and pseudo- -pseudoxanthoma elasticum. Elastosis perforans serpiginosa is a rare perforating disease characterized by transepidermal elimination of ...
Rui Pedro Santos +2 more
doaj +1 more source
Peptide toxins that adopt the inhibitory cystine knot (ICK) scaffold have very stable three-dimensional structures as a result of the conformational constraints imposed by the configuration of the three disulfide bonds that are the hallmark of this fold.
Stephen McCarthy +4 more
doaj +1 more source
The in vitro loss of penicillamine in plasma, albumin solutions, and whole blood: Implications for pharmacokinetic studies of penicillamine [PDF]
The recent development of a high performance liquid chromatography assay method for the analysis of penicillamine in biological samples such as plasma, whole blood, and urine has provided a specific and sensitive assay method to aid in the study of ...
Bergstrom, Richard F. +2 more
core +1 more source
Pulmonary involvement in systemic sclerosis due to therapy and as a complication
(SS), similar to other connective tissue diseases. Sometimes lung disease may be a side effect of antirheumathic drugs. We report a case of a patient affected by SS, with isolated pulmonary hypertension, who developed bronchiolitis secondary to ...
F. Chiappini, A. Zoli, L. Maugeri
doaj +1 more source
Chelant agents are the mainstay of treatment in copper-associated hepatitis in humans, where D-penicillamine is the chelant agent of first choice. In veterinary medicine, the use of D-penicillamine has increased with the recent recognition of copper ...
Michela Pugliese +6 more
doaj +1 more source

