Results 31 to 40 of about 16,893 (203)

D-Penicillamine Induced Degenerative Dermopathy in a Patient with Wilson Disease

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018
D-penicillamine induced degenerative dermatosis include, among others, elastosis perforans serpiginosa, and pseudo- -pseudoxanthoma elasticum. Elastosis perforans serpiginosa is a rare perforating disease characterized by transepidermal elimination of ...
Rui Pedro Santos   +2 more
doaj   +1 more source

D-Penicillamine: The State of the Art in Humans and in Dogs from a Pharmacological and Regulatory Perspective

open access: yesAntibiotics, 2021
Chelant agents are the mainstay of treatment in copper-associated hepatitis in humans, where D-penicillamine is the chelant agent of first choice. In veterinary medicine, the use of D-penicillamine has increased with the recent recognition of copper ...
Michela Pugliese   +6 more
doaj   +1 more source

Rhabdomyolysis and muscle necrosis induced by lead poisoning

open access: yesAdvanced Biomedical Research, 2020
A case is presented on a 40-year-old male with chronic lead poisoning with loss of consciousness, rhabdomyolysis, and acute renal failure after occupational exposure.
Behnaz Ansari   +4 more
doaj   +1 more source

A Chemical Biology Approach to Probing the Folding Pathways of the Inhibitory Cystine Knot (ICK) Peptide ProTx-II

open access: yesFrontiers in Chemistry, 2020
Peptide toxins that adopt the inhibitory cystine knot (ICK) scaffold have very stable three-dimensional structures as a result of the conformational constraints imposed by the configuration of the three disulfide bonds that are the hallmark of this fold.
Stephen McCarthy   +4 more
doaj   +1 more source

Penicillamine‑induced pemphigus

open access: yes, 1982
Penicillamine therapy has been associated with a variety of autoimmune disorders, including pemphigus vulgaris and pemphigus foliaceus. The late scaling rash or oral ulcerations associated with penicillamine may represent the superficial erosions of ...
Schupbach, Curtis   +4 more
core   +1 more source

The pharmacokinetics of penicillamine in a female mongrel dog [PDF]

open access: yes, 1981
The pharmacokinetic parameters of D-penicillamine were investigated by administering four intravenous bolus doses, four oral doses, and six constant rate intravenous infusions to a female mongrel dog at dosages comparable to 250, 500, 750, and 1000 mg in
Bergstrom, Richard F.   +2 more
core   +1 more source

Thrombokinetics in Patients with Rheumatoid Arthritis Treated with D-Penicillamine [PDF]

open access: yes, 1984
The mechanism of D-penicillamine induced thrombocytopenia in rheumatoid arthritis was investigated by measuring platelet life-span and platelet production rate in 2 groups of rheumatoid arthritis patients treated with 250-750 mg/day D-penicillamine, 14 ...
Gallus, A. S.   +5 more
core   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu   +7 more
wiley   +1 more source

Mechanistic, energetic and structural studies of single-walled carbon nanotubes functionalized with penicillamine [PDF]

open access: yesJournal of the Serbian Chemical Society, 2018
Using the density functional theory, the possible non-covalent interactions and six mechanisms of covalent functionalization of the drug penicillamine with functionalized carbon nanotubes (CNT) were investigated.
Shaki Hosein   +4 more
doaj   +1 more source

Erweiterung der Peptidligation auf Saure pH‐Bereiche und Schnittstellen mit Glykosylierten und Phosphorylierten Aminosäuren

open access: yesAngewandte Chemie, EarlyView.
Ein pyridinhaltiges Ligationsauxiliar beseitigt einen wesentlichen Engpass der Peptidligationschemie. Der für die Ligation nutzbare pH‐Bereich von 2,0–7,5 hilft, Epimerisierung zu vermeiden. Die native chemische Ligation (NCL) verläuft an praktisch jeder Ligationsstelle, einschließlich Reaktionen an β‐verzweigten sowie O‑glykosylierten oder O ...
Sebastian Trunschke   +5 more
wiley   +1 more source

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