Results 31 to 40 of about 15,104 (214)

The pharmacokinetics of penicillamine in a female mongrel dog [PDF]

open access: yes, 1981
The pharmacokinetic parameters of D-penicillamine were investigated by administering four intravenous bolus doses, four oral doses, and six constant rate intravenous infusions to a female mongrel dog at dosages comparable to 250, 500, 750, and 1000 mg in
Bergstrom, Richard F.   +2 more
core   +1 more source

Application of 9.4T MRI in Wilson Disease Model TX Mice With Quantitative Susceptibility Mapping to Assess Copper Distribution

open access: yesFrontiers in Behavioral Neuroscience, 2020
In the current study, we used 9.4-tesla magnetic resonance imaging (9.4T MRI) and inductively coupled plasma mass spectrometry (ICP-MS) to investigate the distribution of copper in the brain samples of a murine model of Wilson’s disease (WD) following ...
Yongsheng Han   +11 more
doaj   +1 more source

Double blind controlled trial of D-penicillamine in patients with primary biliary cirrhosis.

open access: yes, 1985
One hundred and eighty nine patients with primary biliary cirrhosis were entered into a double blind, placebo controlled randomised trial starting in January 1978 to assess the therapeutic value of d-penicillamine 1200 mg daily.
Tygstrup, Niels   +7 more
core   +1 more source

Thrombokinetics in Patients with Rheumatoid Arthritis Treated with D-Penicillamine [PDF]

open access: yes, 1984
The mechanism of D-penicillamine induced thrombocytopenia in rheumatoid arthritis was investigated by measuring platelet life-span and platelet production rate in 2 groups of rheumatoid arthritis patients treated with 250-750 mg/day D-penicillamine, 14 ...
Gallus, A. S.   +5 more
core   +1 more source

Chiral Separation of rac-Propylene Oxide on Penicillamine Coated Gold NPs

open access: yesNanomaterials, 2020
The surfaces of chemically synthesized spherical gold NPs (Au-NPs) have been modified using chiral L- or D-penicillamine (Pen) in order to impart enantioselective adsorption properties.
Nisha Shukla   +2 more
doaj   +1 more source

Zinc oxide/Vancomycin-based Electrochemical Chiral Sensor for the Recognition of Penicillamine Enantiomers

open access: yesInternational Journal of Electrochemical Science, 2020
In this study, an electrochemical chiral sensor based on Zinc oxide/vancomycin-modified indium tin oxide glass substrate (ZnO/Van/ITO) was successfully fabricated and used in the chiral recognition of penicillamine (Pen) enantiomers.
Ruzniza Mohd Zawawi   +1 more
doaj   +1 more source

Determination of penicillamine, tiopronin and glutathione in pharmaceutical formulations by kinetic spectrophotometry

open access: yesActa Pharmaceutica, 2021
A novel and simple method for the determination of penicillamine (PEN), tiopronin (mercaptopropionyl glycine, MPG) and glutathione (GSH) in pharmaceutical formulations by kinetic spectrophotometry has been developed and validated.
Kukoc-Modun Lea   +2 more
doaj   +1 more source

D-Penicillamine for preventing retinopathy of prematurity in preterm infants

open access: yes, 2013
Background The rate of retinopathy of prematurity (ROP) in moderately premature infants has decreased dramatically with improved care in the neonatal intensive care unit.
Kumar Manoj, Qureshi Mosarrat J.
core   +1 more source

Late‐Onset Rheumatoid Arthritis and Air Pollution in the Multiethnic Cohort

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the effects of ambient air pollution on rheumatoid arthritis (RA) incidence in a racially and ethnically diverse population. Methods This analysis included 42,152 California Multiethnic Cohort participants, aged ≥65 years (>70% African American and Latino adults) who were enrolled in the Fee For Service component of Medicare (2001–
Anna H. Wu   +14 more
wiley   +1 more source

DFT-QTAIM Study of Gold Nanoparticles and Cyclic Peptide as Effective Drug Nanocarriers

open access: yesOrbital: The Electronic Journal of Chemistry, 2020
In this study, cyclic peptide (CP) with cyclooctaglycine model and gold nanoparticles (AuNP) with Au6 cluster model were used to examin the function of penicillamine (PCA) drug on ten different configurations of cyclic peptide-gold nanoparticles (CPAuNP).
Bahareh Khoshbayan   +3 more
doaj   +3 more sources

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