Results 51 to 60 of about 22,986 (208)

Validity of D-penicillamine in experimental cerebral vasospasm therapy

Interdisciplinary Neurosurgery
Background: Cerebral vasospasm is a reversible vessel constriction following subarachnoid hemorrhage. Immunoreactive and inflammatory mechanisms induce long-term vasoconstriction and vessel dilatation inhibition.
Ersin Haciyakupoglu, Evren Yüvrük, Sebahattin Haciyakupoglu, Milos Arsenovic, Erol Akgül, Dervis Mansuri Yilmaz, Sait Polat   +6 more
doaj   +1 more source

Bacillary Angiomatosis by Bartonella Quintana in an HIV-Infected Patient [PDF]

, 2000
Bacillary angiomatosis and bacillary peliosis are opportunistic infections caused by Bartonella henselae and Bartonella quintana, which occur in patients with late-stage infection.
Afonso, A, Bacellar, F, Cardoso, J, Cardoso, O, Machado, J, Marston, E, Proença, R, Rodrigues, P, Santos, R   +8 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

Chemistry – A European Journal, EarlyView.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

Synthesis and Characterization of Gold Chiral Nanoparticles Functionalized by a Chiral Drug

Nanomaterials, 2023
Inorganic chiral nanoparticles are attracting more and more attention due to their peculiar optical properties and potential biological applications, such as bioimaging, therapeutics, and diagnostics.
Simona Bettini, Michela Ottolini, Donato Valli, Rosanna Pagano, Chiara Ingrosso, Maarten Roeffaers, Johan Hofkens, Ludovico Valli, Gabriele Giancane   +8 more
doaj   +1 more source

Safety, Tolerability, and Pharmacokinetics of GMDTC for Cadmium Poisoning: A Randomized Phase 1a/1b Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Cadmium exposure causes serious health consequences; however, there is no clinically approved antidote for cadmium poisoning. This Phase 1a/1b trial aimed to investigate safety, tolerability, and pharmacokinetics of Sodium (S)‐2‐(dithiocarboxylato((2S,3R,4R,5R)‐2,3,4,5,6‐pentahydroxyhexyl) amino)‐4‐(methylthio) butanoate (GMDTC), a novel chelating ...
Xuefeng Ren, Wei Hu, Xiaobin Deng, Rong Ma, Fang Pei, Xushen Chen, Xuemei Wang, Jixin Tang, Yan Lai, Shangming Pan, Zhiyong Zhong, Sheng Fu, Huamin Yuan, Juan Yuan, Chuntao Huang, Yuan Zeng, Xiaodong Ying, Guanghui Dong, Jinxin Zhang, Jinyuan Zhao, Kangguang Lin, Xiaojiang Tang   +21 more
wiley   +1 more source

Comparison of the Effectiveness and Safety of d-Penicillamine and Zinc Salt Treatment for Symptomatic Wilson Disease: A Systematic Review and Meta‐Analysis

Frontiers in Pharmacology, 2022
Background: Pharmacological therapy is currently the main treatment method for patients with Wilson disease (WD). We aimed to evaluate the efficacy and safety of the common treatment regimens in these patients.Methods: We conducted a systemic review and ...
Shan Tang, Li Bai, Li Bai, Wei Hou, Zhongjie Hu, Xinyue Chen, Jing Zhao, Chen Liang, Wei Zhang, Zhongping Duan, Sujun Zheng   +10 more
doaj   +1 more source

Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao, Song Wang, Yuechao Yao, Yibo Dou   +3 more
wiley   +1 more source

Synthesis and anti-intracellular Copper overload evaluation of Nanoconjugated D-penicillamine –Dendrimer in Wilson’s model cells

مجله دانشگاه علوم پزشکی گرگان, 2016
Background and Objective: Wilson’s disease (WD) is caused by mutation to the cooer-transporting gene ATP7B. Chelation therapy is the main protochol of treatment for patients with Wilson’s disease.
Fani N, Shafiee Ardestani M, Yaghmaei P, Assadi A, Barzegar Behrouz A   +4 more
doaj  

COMPARATIVE OF NATURAL ZEOLITE – CLINOPTILOLITE ELIMINATION OF METAL IONS/ESPECIALLY Cu (II) WITH D-PENICILLAMINE FROM BIOLOGICAL ENVIRONMENTS

Rudarsko-geološko-naftni Zbornik, 2021
Clinoptilolite is used as an adsorbent to remove heavy metal cations due to its function as a molecular sieve. This molecular sieve characteristic has made it possible to study the efficiency of clinoptilolite and D-Penicillamine in a comparative way in ...
Abdollah Forughirad, Ataallah Bahrami, Khalil Farhadi, Anahita Fathi Azerbaijani, Fatemeh Kazemi   +4 more
doaj